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General situation of Hefei cubic pharmaceutical co., ltd.
Hefei Cube Pharmaceutical Co., Ltd. is a high-tech enterprise engaged in drug production and research and development, located in Hefei National High-tech Industrial Development Zone. The company has established seven GMP production lines for tablets, granules, capsules, injections, ointments, gels and APIs, and owns 2/kloc-0 kinds of Chinese medicines and chemicals such as felodipine sustained-release tablets, paeonol ointment, Kunning granules and Xiaoer Huatan Zhike granules. The company's product research and development is based on separation technology and the main direction is slow and controlled release technology. In the research of separation technology, an industrial plant with an annual output of 7000 tons of crude drugs was built, which was broken by wall and leached by membrane ring. In terms of sustained and controlled release technology, there is a leading osmotic-controlled release production line in China, and the products are cubic & reg felodipine, the first felodipine osmotic pump preparation listed internationally, with independent intellectual property rights, and more than ten kinds of drugs have been successfully developed in cardiovascular, digestive, gynecological and diabetes, psychiatry and dermatology.

Hefei Cube Fine Chemical Co., Ltd., a subsidiary company, is a high-tech enterprise specializing in organic synthesis, specializing in the research and production of pharmaceutical intermediates and fine chemicals, and can carry out special reactions such as fluorination, photochemical reaction, hydrogenation, high temperature and high pressure. The company has built the largest deoxyuridine production line in China. The main products are deoxyuridine, 2- deoxyuridine, capecitabine, morpholinone, 5- fluorouracil nucleoside and azelastine hydrochloride. The company has maintained long-term and good cooperative relations with China University of Science and Technology, Anhui College of Traditional Chinese Medicine, School of Pharmacy and other scientific research institutes. * * * Developed a number of high-tech products with high technology content and good market prospects.

Jinzhai Rubik's Cube Pharmaceutical Co., Ltd., a subsidiary company, is located in Jinzhai County, Dabie Mountain, which is rich in medicinal resources, and specializes in the extraction and separation of effective components from natural plants. With the most advanced main equipment in China, such as pretreatment, extraction, column chromatography, concentration, extraction, crystallization and drying, the annual production capacity of medicinal materials can reach 7000 tons. The broken wall and broken membrane-annular countercurrent leaching production line jointly developed by the company and Tsinghua University is the first application in Chinese medicine industry. The company passed GMP certification in 2004, and established thousands of acres of Chinese herbal medicine planting base according to GAP requirements. Gradually form a modern Chinese medicine enterprise integrating Chinese medicine planting, deep processing, research and development and domestic and foreign trade.