The laboratory takes microbial technology directly related to the sustainable development of human society as the main research object, and focuses on studying and utilizing various technical means, including modern biotechnology such as genetic engineering and metabolic engineering, screening new strains of microorganisms with various special functions, studying physiological and metabolic activities of microorganisms, and developing new technologies and techniques for utilizing microbial functions. The main research work includes: (1) research on biomass resource transformation technology, including basic research on microbial degradation mechanism of lignocellulose, screening and transformation of lignocellulose degrading bacteria and their enzymes, production and application technology of related enzyme preparations, degradation and transformation of lignocellulose resources such as industrial and agricultural wastes such as crop straws by microbial technology, fermentation to produce chemical raw materials such as alcohol and organic solvents and useful products such as feed and biogas, and production of feed additives and hydrogen energy by photosynthetic bacteria. (2) Research on resources and environmental microbial technology, focusing on the development of difficult-to-mine mineral resources (such as low-yield oil wells, low-grade metal mines and tailings after secondary oil recovery), the treatment of environmental pollutants (wastewater, waste gas and waste residue), and the research on cleaner production technology (bacterial desulfurization technology, biological pulping technology, enzymatic deinking technology of waste paper, etc.). ), develop environmental protection products (biodegradable plastics, biological pesticides, biological fertilizers, etc.). ) and the development of the marine environment. (3) Research on new fermentation products and technologies, such as new drugs (glutamine, Flammulina velutipes, L- carnitine, etc. ), food or feed additives (nisin, feed probiotics, photosynthetic bacteria preparations), enzyme preparations (lipase, pectinase, isoamylase, etc. ), functional foods, physiologically active substances, antibacterial agents, biopolymers, biotransformation technologies of fine chemical products, etc. (4) Molecular biotechnology research, using modern biotechnology such as genetic engineering, protein engineering, metabolic engineering, etc. , purposefully transform or even create new biological functions, providing the necessary premise for developing new microbial technologies. For example, the construction of autotrophic thiobacillus leaching with anti-arsenic function, Saccharomyces cerevisiae production strain with killing activity, and the establishment of gene transfer system for efficient expression of filamentous fungi; (5) Biochemical engineering technology research, including quantitative physiology, metabolic flux distribution analysis, biological process dynamics model construction, computer optimization control technology of fermentation process, new fermentation technology (such as fed-batch culture technology, continuous fermentation technology, immobilized cell culture technology, high-density culture technology, fermentation and separation coupling technology), new biochemical reactor development, biochemical separation technology, etc.