At present, he is an associate professor and tutor of master students in the Department of Life Sciences, School of Biological Sciences and Engineering, Hebei University of Science and Technology.
Han Chunyu incident is a series of events in which Han Chunyu published papers in top academic journals and the experimental results were questioned because they could not be repeated. Han Chunyu voluntarily withdrew his paper and accepted the investigation:
2065438+On May 2, 2006, Han Chunyu, as a correspondent, published a research achievement in the top international journal Nature Biotechnology, that is, he invented a new gene editing technology-Ngago-GDNA, which challenged the most fashionable technology-CRISPR-Cas9.
After the publication of the paper, it has aroused strong concern at home and abroad, and even been praised by some media as "Nobel Prize-winning" experimental results. But not long after, the content of the paper caused controversy: some people suggested that Han Chunyu's experiment could not be repeated, others said it could be repeated, and they argued with each other endlessly, making it difficult to draw a conclusion. ?
On June 9, 2007, 65438+2007, 65438+2007, Nature-Biotechnology issued the latest statement, pointing out that the journal has obtained new data about the repeatability of Han Chunyu's experiments, and it is necessary to investigate these data.
On August 3rd, 20 17, Nature-Biotechnology published a statement saying that the Han Chunyu team voluntarily applied to withdraw its paper published in the journal on May 2nd, 20 16.
On the evening of August 3, 2065438, Kloc-0, Hebei University of Science and Technology announced the investigation and handling results of Han Chunyu's team's retraction, saying that Han Chunyu's team had not been found to be subjectively fraudulent.
Extended data:
According to the paper, the experiment was independently operated by researchers in different laboratories, but the experimental results did not prove that NgAgo had any genome editing activities. Huang Zhiwei told reporters that his laboratory has repeated it many times, but it has never found the effect of "cutting" and failed to get the expected results.
In addition, the paper also questioned Han Chunyu's previous statement that "superb experimental skills" are needed to reproduce the results of the paper, and repeated experiments are unsuccessful, probably because NgAgo's activity is very sensitive to mycoplasma or bacteria in the culture.
According to the paper, neither the initial published steps nor the updated information on the website of Addgene, a global non-profit organization for scientists, seem to involve any steps that seem to require "excellent experimental skills".
At the same time, it is pointed out that it is impossible for an independent laboratory to contaminate all cells, resulting in consistent negative results.
At the end of this paper, scholars mentioned that they hoped Han Chunyu could clarify the uncertainty of NgAgo and provide the details needed to repeat the experimental results.
References:
Baidu Encyclopedia-Han Chunyu