Bedsore (pressure sore) is also called pressure sore. Bedsore is a long-term local compression of the body, which hinders blood circulation and causes blisters, ulcers or gangrene in the skin and subcutaneous tissue due to ischemia. Generally speaking, patients who stay in bed for a long time, are inconvenient to turn over, and have limb sensory disorders are prone to appear. Excessive emaciation, obesity, edema and arteriosclerosis are all easy to promote the formation of bedsores. Treatment should be started as soon as possible, and the principle is to immediately stop the oppression of the affected area, promote local blood circulation, and strengthen wound treatment. First-degree bedsore can be given regular massage, changing body position, local alcohol application and baking. If the inflammation is obvious, wet compress can be applied with 0.5% neomycin solution. Second-degree bedsore can be coated with antibiotic ointment and covered with sterile gauze. Third-degree bedsore must be cleared of carrion and debrided repeatedly. For patients with small ulcers, 0.5% silver nitrate can be used externally to eradicate infection, and Kangfuxin drops can be used to promote granulation tissue formation. Skin transplantation can be used for patients with large ulcers. For gangrenous bedsore, the necrotic tissue should be completely removed by adequate drainage. At the same time, high protein diet should be given, and severe patients should be strengthened with supportive treatment, and whole blood should be infused when necessary to correct the tendency of nitrogen retention. Wound pus is often cultured and drug sensitive, and appropriate antibiotics are selected for external use. Combined with widespread infection, systematic use of antibiotics. Strengthen the sense of responsibility for bedridden patients and adhere to the regular nursing system. Avoid local compression, turn over every 2~4 hours and massage the compressed part in time. If necessary, some thin and compressible parts can be hung. Keep the skin clean and dry, and keep the bed flat, tidy and soft. Improve local blood circulation, often massage the local area with 50% alcohol, and apply talcum powder after massage, 2~4 times a day. According to the different stages of the development process, the clinical manifestations can be divided into three degrees: first, the earliest manifestation of bedsore, local erythema, edema, numbness or tenderness, which can not be recovered after relieving the pressure, but can be improved within a few days after treatment. Second degree: the epidermis is purple-black, or blisters or loose skin fall off, forming a rotten surface. Third degree: ulcer formation, shallow to subcutaneous fat layer, deep to bone tissue, after secondary infection, pus is much and smelly. According to Y-K classification, it is divided into: Class Ⅰ A: erythema lasts for 30 minutes to 24 hours; Class I B: erythema lasts for more than 24 hours. Grade II: Epidermal and/or dermal ulcers do not touch subcutaneous fat. Grade ⅲ: the ulcer is deep and subcutaneous fat. Grade ⅳ: deep to muscle and fascia. Grade ⅴ: Deep to the bone surface. Grade ⅵ: Joint cavity involved. The course of the disease gradually changed from light to heavy. For example, the deep and shallow tissues in the compressed part are simultaneously ischemic and anoxic, which leads to the sudden occurrence of bedsore, that is, "gangrenous bedsore". The local skin is dark purple spots at first, and the finger pressure does not subside, accompanied by severe pain or numbness. The patch can die after rapid expansion, losing pain, and the necrotic tissue is covered with scab skin, which forms an ulcer after falling off, reaching the muscle layer or bone. Bedsore is often accompanied by bacterial infection, especially sepsis caused by local cellulitis, abscess, periosteum, osteomyelitis and Pseudomonas aeruginosa infection, which quickly aggravates the cachexia of patients. Patients diagnosed as coma and paralysis are in bed for a long time. Weak patients often press the bony processes such as sacrococcygeal, ankle and heel without muscle covering or muscle thinning, and then they die to form ulcers, which are often accompanied by bacterial infection, persistent anemia and different degrees of nitrogen retention or calcium deposition and aggravate the patient's original diseases. Differential diagnosis the cause of long-term oppression and concentration in a small area of the body is enough to cause local blood circulation to be oppressed, resulting in tissue hypoxia and injury or vascular necrosis. If the compression continues, the progress of the lesion can make the full-thickness skin necrotic and missing. Ulcer often leads to bacterial infection. Due to the congestion of capillaries and veins at the base and edge of ulcer, a large number of granulation tissues are gradually formed, and the effect of antibiotic system application is often greatly weakened. Therefore, the ulcer or gangrene area can rapidly penetrate and expand under the skin, and its diameter can reach 3~6 cm after a few days. The infiltration range can reach 8~ 10cm at the edge of ulcer appearance, and the deep development can involve periosteum and even bone, causing focal periostitis or extensive osteomyelitis. How to prevent bedsore in patients with cerebrovascular disease? Patients with cerebrovascular disease are prone to skin ulceration, tissue necrosis and bedsore due to hemiplegia, long-term bed rest, local tissue compression and blood circulation disorder. Therefore, it is necessary to strengthen skin care and prevent bedsores. The specific measures are as follows: (1) Turning over frequently can prevent patients from being pressed in the same place for a long time. Generally, turn over once every two hours, but when turning over, you should move gently to avoid dragging, pulling and pushing, so as not to scratch your skin. Sponge pads should be added to the bony process, and rubber bands can be added if possible to reduce local compression. (2) change frequently. Patients with incontinence should remove excreta in time to avoid skin irritation due to dampness. Clothes, bedding, sheets, etc. Those contaminated by excrement should be replaced in time to keep local skin clean and sanitary to avoid infection. (3) Always keep the bed clean, flat, dry and soft. Every time you turn over, you should pay attention to tidying up the bed surface to make it smooth and free of sundries, so as not to scratch your skin. (4) Check the locally compressed skin regularly every time you turn over, and take active measures immediately to prevent the disease from developing. (5) Regular massage is mainly to massage the prominent bone parts that are prone to bedsore. When massaging, the palm is close to the skin, from light to heavy, and then from heavy to light, doing circular massage. Use 5% alcohol or safflower alcohol after massage. Wound oil or skin lotion can be used in winter to promote local blood circulation, improve nutrition and prevent bedsore. (6) Strengthening malnourished skin has poor tolerance to crush injury and is prone to bedsore. Therefore, we should give a high-protein and high-vitamin diet and take enough water to increase the skin's resistance.