Male, associate professor, born in June 1953, Hunan native, graduated from Chengdu University of Technology. 1981.9-1987.7 assistant professor, 1988.8- 1995.9 lecturer, 1995.5438+00- associate professor, School of Pharmacy, Chongqing Medical University. Mainly engaged in the ways and processes of biocatalysis and transformation, optimizing the biocatalysis reaction process, establishing a biocatalysis and transformation system with high selectivity, high stability and high efficiency, researching and establishing a non-aqueous biocatalysis technology system and a whole-cell catalysis system, and researching and developing important chiral chemicals, pharmaceutical intermediates, drugs and new preparations applied to the chemical and pharmaceutical industries. He has participated in the research of provincial and ministerial-level projects, among which the ministerial-level project "Preparation of Agarose Coated Microcapsule Activated Carbon CAAC-II for Hemoperfusion" won the second prize of Sichuan Science and Technology Progress, and the key project of Chongqing Science and Technology Commission "New Technology of Fructose Diphosphate" won the third prize of scientific and technological progress in Daxing Pharmaceutical Industry, and won the certificate of scientific and technological achievements completion in Chongqing (second finisher) and the honorary certificate issued by Chongqing Municipal People's Government (second finisher). Participated in compiling 2 textbooks published by People's Health Publishing House, published more than SCI, EI and CSCD papers 10 at home and abroad, and now there are 3 graduate students.

Zhang Liangke, male, doctor of pharmacy, associate professor, tutor for master students, expert in evaluation of Chongqing Science and Technology Committee, expert in continuing education and training of licensed pharmacists in Chongqing, and editor of China Journal of Tissue Engineering and Clinical Rehabilitation. June 1998 Graduated from Sichuan University with a master's degree in fine organic synthesis, majoring in applied chemistry. 1998-200 1 engaged in new drug development in Sichuan Institute of Antibiotic Industry. In June, 2004, he graduated from West China College of Pharmacy, Sichuan University with a doctorate. Since July 2004, I have worked in the School of Pharmacy of Chongqing Medical University. To undertake undergraduate courses in pharmacy, biopharmaceutics and pharmacokinetics, pharmaceutical technology, pharmaceutical dosage forms and clinic, as well as postgraduate courses in new dosage forms and new technologies.

In recent years, he has undertaken many national and provincial related topics and published more than ten CSCD core journals and SCI papers.

The related papers published in recent years are as follows:

1) Zhang Liangke, Yuan Pei, Tian Rui, Xu Ling, Yu Ruijie, Study on swelling and drug release properties of different ionic crosslinked pectin gel pellets, Journal of Biomedical Engineering, 2009, (accepted)

2) Zhang Liangke,,, Sun,, Release Effects of Different Pectin Gel Pellets on Bovine Serum Albumin [J], China Journal of Pharmacy, 2008,43 (18):1407-1410.

3) Zhang Liangke, Yuan Pei, zhangyan, Cheng Hongwei, Effects of different ionic crosslinking agents on swelling and drug release properties of alginate gel pellets, China Pharmaceutical Journal, 2008,43 (8): 606-609.

4) Zhang Liangke, zhangyan, Tian Rui, Lai Jiejuan, Investigation on the factors influencing the release of acemetacin calcium alginate gel pellets, China Hospital Pharmaceutical Journal, 2007,27 (12):1671-1674.

5) Zhang Liangke, Hou, Song Kangrong, Distribution and Pharmacodynamics of Mitoxantrone Albumin Nanoparticles Mediated by Folate Receptor, China Journal of Pharmacy, 2007,42 (9): 676-678.

6) Zhang Liangke, Hou, Song Kangrong, Preparation and Evaluation of Albumin Nanoparticles, China Pharmaceutical Journal, 2007,42 (5): 365-367.

7) Zhang Liangke, Hou, Mao, Song Kangrong, Receptor-mediated targeting of mitoxantrone albumin nanoparticles to tumor cells, Journal of Sichuan University (Medical Edition), 2006,37 (1): 77-79.

8) Zhang Liangke, Hou, Song Kangrong, Preparation and in vitro properties of folic acid-coupled mitoxantrone albumin nanoparticles, China Journal of Pharmacy, 2005,40 (10) 763-765.

9) Liang Kezhang, Hou, Mao,,, etc. Uptake of folic acid-coupled albumin nanoparticles into SKOV3 cells, International Journal of Pharmacy, 2004,287 (2):155-162 sci.

10) Zhang Liangke, Hou Mao, Song Kangrong, Preparation of folate-coupled albumin nanoparticles, Journal of Biomedical Engineering, 2004,21(2): 225-228.

1 1) Zhang liangke, Huang Yu, synthesis of isoleucine by alkylation under microwave irradiation, Journal of Sichuan University (Engineering Edition), 2000 (1): 2 1-24.

12) Zhang liangke, Chen Xiru, Huang Yu, synthesis of phenylalanine by alkylation under microwave irradiation, journal of Sichuan university (engineering edition), 1999 (5): 53-57.

13), Hou, Zhang Liangke, He Junyao, Transcutaneous Lymphatic Targeting Vincristine Transporter, Journal of Pharmacy, 2007,42 (10):15438+0065438.

14) Mao Shijun, Hou, He, Zhang Likai, Wei Deping, Bi Yuqiang, Jin Hong. Uptake of glycyrrhizic acid modified albumin nanoparticles by primary cultured rat hepatocytes. World Journal of Gastroenterology. 1 1(20):3075-9SCI

15) Mao, Hou, Zhang Liangke, Bi, Jiang Bin, Preparation Technology of Glycyrrhizic Acid Liver Cell-Targeted Surface Modified Albumin Nanoparticles, Journal of Pharmacy, 2003,38 (10): 787-790.

16) Mao, Hou, Zhang Liangke, Zhang, Qiao Xiaorong, He Ru, Preparation of Valaciclovir Albumin Nanoparticles Modified by Glycyrrhizic Acid and Its Liver Targeting Study, Journal of Biomedical Engineering, 2004,21(4): 570-574.

17) Mao, Hou, Zhang Liangke, Preparation of hepatocyte-targeted glycyrrhetinic acid surface-modified liposomes, China Journal of Traditional Chinese Medicine, 2003,28 (4): 328-331.

Contact information: zlkdyx @126.com.

Wang Chi

Male, 48 years old, doctor, associate professor.

1982 graduated from the Department of Chemistry of Sichuan University with a bachelor of science degree in physical chemistry. Assigned to Sichuan Paper Industry Research Institute for scientific research. 1993 studied in Chongqing medical university with a master's degree in biomedical engineering, 1996 graduated with a master's degree in medicine. Stay in school and teach in the chemistry teaching and research department of the basic medical college of heavy medicine. 200 1 Associate Professor. From 200 1 to 2004, he studied for a doctorate in the Department of Clinical Laboratory of Chongqing Medical University.

Participated in the research project of new drug development of Heavy Drugs and Heavy Beer Group, and was one of the main research members; Completed the project of Chongqing Municipal Health Bureau "Research on the Creation of Fructose Diphosphate New Drugs" and became one of the main members. In 2000, "D- fructose-1, 6 sodium magnesium diphosphate, its preparation method and its application in the preparation of drugs" won the invention patent of People's Republic of China (PRC) and China National Intellectual Property Administration (patent number: 98112218.3). From 2005 to 2007, the doctor initiated a research project: research on polymers as drug carrier materials.

In 2000, he participated in the seminar on drug research and drug design organized by the Ministry of Education in Tsinghua University. 200 1 Ph.D. in clinical laboratory diagnostics, Chongqing Medical University.

The first author published a paper:

1. Study on dynamic stability of magnesium fructose diphosphate, Journal of Chongqing Medical University, 2000.25 (2); 1 15- 1 17。

2. Study on the preparation of fructose-1 6 calcium diphosphate, chinese journal of medicinal chemistry, 2000.10 (2); 1 10- 1 12。

3. Determination of fructose-1 6 diphosphate by aldolase -DNPH colorimetry, Journal of Biomedical Engineering, 2000,438+07 (3); 249-25 1。

4. Effect of magnesium fructose diphosphate on hemodynamics in rats with acute myocardial ischemia induced by pituitrin. Journal of Sichuan Physiological Sciences,1999+0 (4); 22。

The second author published a paper:

1. study on the inhibitory effect of common anti-tumor drugs on the proliferation of laryngeal carcinoma KBv200 cells, journal of clinical trials, 2003; 2 1(4):45-47

2. Effects of anti-tumor drugs and verapamil on the expression of P- glycoprotein in KBv200 cells, Journal of Clinical Laboratory, 2003; 2 1(4): 10

3. Effects of antineoplastic drugs and matrine on the expression of P- glycoprotein in KBv200 cells, Journal of Clinical Laboratory, 2003; 2 1(4): 10

Huang Hua

1982 graduated from Sichuan medical college with a bachelor's degree in chemistry and pharmacy in July.

1August 1982 to1August 1999,165438+1October, engaged in technical management of pharmaceutical preparation production and research and development of new pharmaceutical preparations in Chongqing No.6 pharmaceutical factory for ten years, and successively worked as workshop technician, factory technician, section chief and director of pharmaceutical research of Chongqing Yaoyou Pharmaceutical Co., Ltd. after the restructuring of this factory.

1999 12 was transferred to the pharmacy teaching and research section of the Department of Pharmacy of Chongqing Medical University as a pharmacy teacher.

Pay attention to the development direction of international advanced medical technology, especially the research trends of new drug release systems and preparation technologies at home and abroad. At the same time, he has rich experience in new drug research and development and management, from pre-clinical research and clinical research such as market research and topic selection, pharmaceutical research and medical research to new drug declaration, and has directly carried out the whole process of new drug research and development, and is familiar with the pharmaceutical laws and regulations and related technologies involved.

Organized and presided over the research and development of several new drugs. As the person in charge of prescription technology, the milk progesterone gel was supported by the National Innovation Fund for Small and Medium-sized Enterprises. The products that occupy an important position in the pharmaceutical market in recent years-reduced glutathione for injection (trade name: Atomolan) with annual sales of single product 1 100 million yuan and alfacalcidol tablets for treating osteoporosis with good economic benefits have been successfully developed. The orally disintegrating tablet of salbutamol, which was researched in cooperation with enterprises, was declared for the first time in China, and obtained the first new dosage form of orally disintegrating tablet "New Drug Certificate" and "Drug Registration Approval" approved by the State Food and Drug Administration of the United States, which filled the domestic blank and has been industrialized at present. Various chemicals, orally disintegrating tablets of traditional Chinese medicine, injections, gels and other dosage forms have been developed and declared.

Published 8 papers in 2004-2006:

1. Effect of surfactants on dissolution of puerarin solid dispersion in vitro [J]. Journal of China Pharmaceutical University, 2004,35 (4): 315-317.

2. Study on bioavailability of orally disintegrating tablets of salbutamol sulfate [J]. China Pharmacy 2004, 15 (9): 55 1-554.

3. Research progress of orally disintegrating tablets [J]. China Hospital Pharmacy Journal 2005,23 (2):167.

4. Active drug loading of liposomes and its research progress [J]. Foreign Journal of Medical Pharmacy 2005,32 (4): 271-274.

5. Progress in preparation technology by solid dispersion method [J]. China Journal of Pharmacy 2005,36 (10): 648-650.

6. Research progress of self-emulsifying drug delivery system [J]. China Pharmacy 2005,16 (19):1499-1501.

7. Preparation and adhesion of nystatin oral adhesive tablets [J]. China Pharmacy 2006,17 (11): 815-817.

8. Research and application of implants [J]. China Pharmaceutical Industry 2006, 15 (6): 3-5.

Zhu didn't find it. Sorry.