Henan Polytechnic University has three campuses, namely, South Campus, North Campus and West Campus.

As of June, 2023, Henan Polytechnic University has three campuses: South Campus, North Campus and West Campus, covering an area of 4 100 mu and a building area of10.4 million square meters. The total value of teaching and research instruments and equipment is 884 million yuan, the total value of fixed assets is 2.598 billion yuan, and there are 3.6 million paper books and 4.87 million electronic books in the collection. There are 23 teaching colleges, Cheng Zheng College, International Education College, Continuing Education College (Safety Technology Training Center), Innovation and Entrepreneurship College, 2 affiliated hospitals and 80 undergraduate majors.