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When pure substances are mixed into a mixture, do the number and types of atoms change? What are the rules?
There is no chemical change in the mixing process. Even if there is, the design molecule does not involve atoms. The change of atoms is called nuclear fusion reaction. There are too many kinds of mixing, most of which are mixed between metals, and there is no certain law, because there are many variables in conditions and temperatures. There is a special college of materials science in the university to study this.