Identification, cloning and recombinant expression of functional genes; Gene function and regulation; Purification and activity of protease; Insect functional gene recombinant nuclear polyhedrosis virus biological insecticide, etc. Supported by key projects of National Natural Science Foundation and 863 projects. 198/kloc-0 graduated from the biology department of southwest normal university in/98, obtained the master's degree in zoology from Shandong university in 1984, and obtained the doctor's degree in entomology from Nanjing Agricultural University in 1997. Since 1984, I have worked in the School of Life Sciences of Shandong University. Mainly engaged in insect physiology, biochemistry and molecular biology research. Representatives of the 12th and 13th People's Congress of Jinan.
1990- 199 1 went to Japan to study cysteine protease; 1998-2000 was awarded the "Postdoctoral Scholarship for Special Projects in Biological Sciences" by the German Government Academic Exchange Conference (DAAD) and went to Germany to study V-ATPase. From 200/kloc-0 to 2002, he was engaged in DNA and protein sequencing, renaturation and purification of recombinant protein inclusion bodies, and expression of foreign genes by Pichia pastoris. In 2005, he went to Japan to study protein omics. (* correspondent):
1., Jing, Juan, Lian, Fan *, cathepsin B-like protease participate in the decomposition of the fat body of the adult cotton bollworm. Insect Physiological and Biochemical Archives 2006,62:1-10.
2. Fan *, He Hongjuan, Juan, 2006, Identification of differentially expressed proteins in molting stage of Helicoverpa armigera larvae. Journal of protein Group Studies, 5, 164- 169.
3. Fan *, Meng, Juan, Jun, Ueda S and Kondo H. 2005, Expression of cathepsin B in embryonic development, Arch Insect Biochemistry. Physiology, 58:39-46
4. Fan *, Wang Jinxing, Xue, Maeda and Hiroshi Kondo, 2005, Analysis of substrate specificity and endopeptide cleavage site of cathepsin B in Helicoverpa armigera, protein Journal, 24: 219–225.
5. Fan *, Wang Jinxing, Xu Xialian, Zhaomin Li and Kang Cuijie. In 2004, molecular cloning and expression pattern of the molting regulatory transcription factor hhr3 of Helicoverpa armigera. Insect Molecular Biology. 13:407-4 12.
6. Zhao *, Li,,,, Harvey Blanks Wave 2003. Efficacy of a new nonsteroidal ecdysone agonist RH-2485 against Helicoverpa armigera: laboratory and field experiments. Crop protection. 22:959-965.
7. Zhao *, Wang Jinxing, Xu, Roland schmid, Helmut Wieczorek, 2002, Molecular cloning and characterization of cathepsin B of Helicoverpa armigera. Molecular Biology of Insects. 1 1:567-575.