In the controllable synthesis of multistage polymers, the principle and realization method of controllable synthesis of dendritic polymers, core-shell polymers and fixed-point graft polymers were studied by combining molecular design with performance design, and the relationship between structure, properties and functions was also studied. At present, he is undertaking two research projects funded by the National Natural Science Foundation. In 2004, he published five papers in advanced materials, macromolecules and polymers.
In the aspect of polymer composite modification, we will continue to carry out basic theoretical and applied research on compatibility, interface characteristics, shape and size control and failure mechanism, life prediction and interfacial molecular bonding state of polymer * * *, and carry out in-depth theoretical research and application development on organic polymer/inorganic hybrid composite mechanism, physical and chemical properties of polymer nanocomposites, molecular tailoring and assembly, etc. At present, he is undertaking two research projects funded by the National Natural Science Foundation, and has published 14 papers in international journals such as Journal of Polymer Science-Series B, Journal of Applied Polymer Science and Polymer Science and Engineering in recent five years. We have established long-term cooperative relations in scientific research and personnel training with large enterprises such as Anhui Guofeng Group, Wanbei Coal and Electricity Group, Anhui Fengyuan Group, Anhui Chlor-alkali Group and Huangshan Yongjia Group, and built several Industry-University-Research engineering centers.
In terms of functional and green polymers (stealth coatings, ultraviolet curing coatings, thermochromic gels, waterborne coatings, waterborne adhesives, amphiphilic coatings), we will carry out basic research and application development of functional polymer materials such as light, heat, electromagnetism, mechanics and biology, and expand the direction of green degradable polymer functional materials and environmentally friendly polymer materials. At present, it undertakes a national natural science foundation project and a large number of research projects entrusted by enterprises. At the same time, acrylic cathodic electrophoretic paint, quick-drying putty and amphiphilic paint have been successfully applied to diesel engines, automobiles, forklifts and air-conditioning industries in Shanghai and Anhui, bringing remarkable economic benefits to enterprises. This series of environmentally-friendly water-based adhesives have been formally produced in enterprises in Hefei and other places, meeting the market demand.
Preparation technology and technology of inorganic functional materials
Inorganic functional materials, including all functional materials except organic polymers and composite materials, play an important role in the development of national economy, and the research and development of their preparation methods have attracted more and more attention from researchers at home and abroad. This direction focuses on the preparation of new mesoscopic materials such as catalyst materials, optical functional materials and mineral materials, and carries out material design and process optimization according to the needs of application process. Combined with the latest trends and research hotspots of chemical engineering, the key problems in the preparation of new mesoscopic materials are solved by using the theory and method of chemical engineering, with the goal of controlling the microstructure and properties of materials by studying the relationship between preparation process, microstructure and properties. On the one hand, traditional chemical engineering technologies, such as supergravity technology, microgravity technology, supercritical technology, hydrothermal technology and membrane technology, are extended to the preparation of new mesoscopic materials; On the other hand, new unit technology and reaction separation integration technology are developed to solve the technical problem of process amplification and realize the large-scale production of related new materials. Through research and innovation, we can not only solve the key problems in the production of new materials, but also promote the development of emerging materials chemical engineering disciplines.
In recent years, our department has successively undertaken 3 projects of National Natural Science Foundation, funded projects of Ministry of Education 1 Excellent Young Teachers, 2 start-up funds of returned overseas students of Ministry of Education, 6 natural science foundations of Anhui Province, international cooperation projects of Anhui Province 1, key scientific and technological projects of Anhui Province 1 and many cooperation projects entrusted by enterprises. From 200/kloc-0 to 2006, more than 20 papers were published 120, including more than 50 SCI papers published in important international academic journals, which were searched by Web of Science and cited by domestic and foreign counterparts for more than 250 times. Apply for 5 invention patents and transfer a number of scientific research achievements. Won the third prize of outstanding scientific and technological achievements in colleges and universities in Anhui Province, and 1 person won the "Anhui Youth May 4th Medal". As a subject with a wide application background, the basic research of electrochemistry often has a strong application orientation, and has important applications in energy, materials, life, environment, nanotechnology and other fields. The research contents of applied electrochemistry involve nonlinear electrochemistry, energy electrochemistry, material electrochemistry, nano-electrochemistry, metal electrodeposition, chemical power supply, electrochemical corrosion and anticorrosion, electrolysis, electrodeposition, bioelectrochemistry, electrocatalytic materials and technologies, nano-functional materials, computational chemistry and so on.
This direction has formed its own characteristics in electrochemical methods and technical applications, material preparation and electrochemical characterization, battery technology and so on. Synthesis of new energy nano-materials, focusing on lithium-ion battery electrode materials and solar battery materials. Nitrides and their composites were prepared systematically, and the supercapacitor properties of nitrides were studied. This work is rarely reported abroad, and there is no related research by other research groups in China. The electrochemical research of supercapacitor materials was carried out earlier in China. A new preparation method of carbon aerogels material is opened up, and a low-cost and high-efficiency preparation process is developed. Make full use of straw as a renewable resource, prepare activated carbon materials with high specific capacitance, solve the environmental and social problems caused by straw burning, and develop new energy storage carbon materials; The research of electrochemical chaos in China has been developed, and the control and synchronization of electrochemical chaos have been realized, which has obvious characteristics and advantages in nonlinear electrochemistry. Using layered silicide and graphite as matrix, organic/inorganic layered nano-composite battery materials were obtained by intercalation and hybridization technology. Combine electrochemical method and biotechnology for biological analysis, combine spectral electrochemical method for electrochemical field analysis, and carry out field analysis in the detection and dynamic process analysis of natural antioxidants, biological hormones and various biological small molecules; Carry out electrochemical deposition, material surface treatment and corrosion inhibitor application, use inorganic-organic hybrid materials for coating protection, and carry out in-depth theoretical research and application development around protection technology.
This direction actively participated in the technological transformation of science and technology enterprises, and the scientific research course cooperated with Huaibei Dongci Group was supported by the Provincial Science and Technology Department and approved as the key project of scientific and technological research in Anhui Province. In the aspect of comprehensive utilization of biomass, Industry-University-Research has been combined with Ningguo City. In the development of supercapacitors, we have formed Industry-University-Research cooperation with Yuanguang Electric Appliance Co., Ltd. The research of copper electrolytic refining has played an important role in improving the copper grade of the largest copper smelting base in China. Actively participated in the anti-corrosion project of Hangzhou Bay Highway Bridge and successfully completed the research, development and implementation of two anti-corrosion projects. The waterproof and anticorrosive materials developed have been used in the protection of Baogong Temple and achieved good results. In recent years, it has undertaken a number of scientific research projects, including the National Natural Science Foundation of Anhui Province, the key science and technology projects of Anhui Province and the key science and technology projects of Hefei City. In recent years, he has published more than 20 papers/kloc-0 in academic journals at home and abroad. He has made important achievements in electrochemical theory and won the third prize of provincial scientific and technological achievements for many times. The focus of this study is the development of fine and special chemicals such as medicine, pesticides, surfactants and their intermediates, as well as the study of fine organic synthesis and biotransformation and their theoretical and technical problems. The production of fine chemicals is the most important part of the chemical industry. The proportion of fine chemicals in chemical industry is over 85% internationally, only about 50% in China, and even lower in Anhui. Fine chemical industry is a technology-intensive and capital-intensive industry, and the profit and tax rate of products is also very high. After nearly 30 years of reform and opening up, China has formed a relatively concentrated fine chemical industry cluster in the eastern coastal areas, which also provides opportunities for the development of Anhui fine chemical industry. With the consumption of fossil resources, the technical demand for producing fine chemicals from biomass is increasingly urgent. Our province is a big agricultural province in the east, with a large output of biomass resources such as agricultural products, which provides raw material guarantee for the production of fine chemicals by biotransformation. Therefore, the research on fine synthesis, biotransformation and their process coupling technology will play a decisive role in improving the technical level of fine chemicals production in our province and even the whole country, reducing environmental pollution and toxic and harmful substances emissions, improving the level of safe production and reducing production costs.
In this direction, combined with the development of modern chemical engineering, the research of reaction separation coupling engineering and biological enzyme engineering has been carried out, and the chlorination reaction engineering technology with independent intellectual property rights and certain advantages has been formed. The gas-liquid chlorination reaction-column separation coupling engineering technology developed has been used in the industrial production of 1200 tons/year dichlorobenzene, 600 tons/year pharmaceutical-grade monochloroacetone and bis (trichloromethyl) carbonate (i.e. triphosgene). The separation engineering technology of reaction tower has also been successfully applied to the industrial production of 5000 tons/year medicinal (tasteless) 1, 2- propanediol. According to the principle of chemical reaction and the basic theory of mass transfer process, the equimolecular two-phase diffusion mass transfer process of organic gas-liquid chlorination reaction was studied, and a brand-new mass transfer (mathematical) model was proposed and established. At present, the coupling engineering technology of toluene para-selective chlorination reaction and separation is being carried out, and the simultaneous saccharification and fermentation technology of immobilized microbial enzymes for producing ethanol and lactic acid is being studied.
In the synthesis of drugs and fine functional chemicals, according to the market demand and development trend at home and abroad, the research on the synthesis of functional fine chemicals such as surfactants and intermediates was carried out, and the research on new methods and technologies of drug synthesis was carried out in combination with the research on generic drugs. The drugs with new structure are mainly "me-too" drugs, which are designed and synthesized. With independent intellectual property rights, the new technical method of triphosgene synthesizing carbonate and isocyanate is at the leading level in China, which has been used to synthesize polycarbonate, diphenyl carbonate, 4- nitrophenyl carbonate, sulfonyl isocyanate and other products, among which triphosgene synthesizing sulfonyl isocyanate has made great contributions to the breakthrough of key production technologies of sulfonylurea herbicides in our province and the whole country. At present, the synthesis of functional products such as hydroxybutanone and its derivatives, biological vanillin and fuel ethanol, the immobilization of cells (enzymes) to produce dextran, the biosynthesis of anticancer drug prodigiosin, the design and synthesis of polymer prodrugs such as water-insoluble drugs and polypeptide drugs are under way. In this direction, modern biotechnology is combined with the basic principle of reaction-separation coupling engineering. Based on the coupling engineering of biological enzyme engineering and reaction separation, aiming at the characteristics and existing problems of biopharmaceutical process, the immobilization method to maintain the activity of microorganisms and enzymes is studied emphatically, and the process of drug synthesis by microorganisms and enzymes is studied by engineering methods. Developed bio-enzyme immobilization technology has begun to provide technical support for biopharmaceutical industry.
The main research contents in this direction include: (1) coupling engineering technology and application of chemical and biopharmaceutical processes; Study on the synthesis of drugs and their intermediates: pharmaceutical polymers and new dosage forms; Biotransformation of natural products by microorganisms and their enzymes: research on enzyme immobilization technology: research on GMP design technology of pharmaceutical engineering.
In the research of producing dextran by immobilized enzyme, a new material and method of immobilized Leuconostoc mesenteroides were formed, and the national invention patent was declared. Leuconostoc mesenteroides was immobilized by alginate-based composite to produce dextran sucrase, and a new process of synthesizing dextran by free enzyme method was introduced. According to the formation mechanism of dextran synthesis, combined with the influence of process engineering conditions on molecular weight and step-by-step research results, a molecular weight adjustment method of enzymatic in-situ fixed-length shearing was proposed. Combined with the coupling engineering technology of reaction and separation, the production regulation of dextran with specific molecular weight for clinical use was basically realized. The study on the enzymatic oxidation of Serratia marcescens and the degradation of easily degradable polyphenols/amines by hydrogen peroxide found that the enzyme that can catalyze the degradation of polyphenols/amines is extracellular enzyme, which basically clarified the mechanism of enzymatic degradation and oxidation. Isoeugenol was transformed with immobilized enzyme to produce vanillin.
In order to solve the obvious irritation of aspirin to gastrointestinal tract and prolong its retention time in vivo, dextran-aspirin coupled polymer drugs were synthesized with dextran as carrier. The drug and polymer are directly combined by chemical bonds to prepare biodegradable sustained-release drugs, so that aspirin can be released from the polymer through hydrolysis or enzymatic reaction. Due to the biodegradability of dextran, dextran-aspirin coupled polymer drugs have intestinal targeting.
Paeonol extracted from Paeonia suffruticosa in Tongling, Anhui Province is used as the effective component, and borneol and borneol inclusion compound are creatively used to form an all-natural daily antiseptic and mildewproof agent combining sudden release and slow release, which provides a new generation of natural, efficient and long-acting mildewproof and moth-proofing agent that is environmentally safe for human body, and has applied for a national invention patent.
In recent years, our company has undertaken and completed a number of cooperation projects entrusted by provincial and ministerial enterprises, such as: the application and development of new technology for producing dextran by immobilized enzyme (Anhui economic and trade science and technology project, 4.5 million); Secondary development and high-tech industrialization of Jinshuibao capsule: production of vanillin by fermentation; design and research of Chinese medicine extraction engineering; design and research of Chinese medicine extraction and preparation engineering; Study on safe and non-toxic mildew and moth-proofing agent: GMP study on the production technology of BCG RNA. Anhui province is rich in mineral resources, including bentonite, alunite, attapulgite, serpentine, potash feldspar, kaolin and so on. But at present, the utilization rate of mineral resources in our province and even the whole country is still low, and there is a lot of room for deep processing and comprehensive development and utilization. Since the Seventh Five-Year Plan, with the support of the National Natural Science Foundation, key science and technology projects in Anhui Province, key scientific research projects in Anhui Province, and key scientific research projects in Hefei City, and with the cooperation of relevant enterprises, we have focused on the physical and chemical properties of nonmetallic mineral resources in China, especially in Anhui Province, including deep processing technology, comprehensive utilization of new technologies, and synthesis and application of mineral materials.
In the past decade, the typical achievements in this direction are:
(1) In the pyrometallurgical processing of minerals, a new method of preparing potassium sulfate by rapid dehydration and decomposition of alunite minerals at high temperature and separating aluminum and silicon by acid melting was obtained. A new mechanism of extracting potassium from potash feldspar is established, and a variety of new processes for preparing potash fertilizer and potassium-containing compound fertilizer from potash feldspar are developed.
(2) In the wet processing of bentonite, serpentine, kaolin and other minerals, a new process of activated acid leaching was obtained, which made the processing process have the characteristics of low energy consumption, less raw material consumption, no environmental pollution, simple technology and equipment, easy industrialization and basically green processing.
(3) In the thermodynamic study of mineral processing, complex silicate minerals are expressed as the sum of possible simple compounds by mineral addition technology, and the standard Gibbs free energy of silicate minerals such as montmorillonite and serpentine is estimated by least square regression method, which provides a basis for the thermodynamic analysis of chemical processing of silicate minerals. In the study of mineral processing kinetics, the reaction model, reaction control steps, macro-kinetics and optimal design of reactor in the main processing procedures of kaolin, serpentine, alunite and other minerals were studied, which laid the foundation for the industrial design of main equipment.
(4) Using modern instruments, it is found that the amorphous silica obtained by treating bentonite and serpentine with inorganic acids has good functionality and remarkable reactivity, which is convenient to synthesize various silicon compounds and use as various functional materials.
(5) In the production of high value-added products from non-metallic minerals, a series of production technologies of magnesium compounds, silicon compounds and aluminum compounds have been developed.
(6) In the aspect of synthesis and application of mineral materials, the preparation and application of micro/mesoporous mineral materials such as pillared clay are studied. On the basis of in-depth study of its structure and properties, the structure of pillared clay was modified by active substances to improve its properties and make it have better catalytic and adsorption properties.
The above achievements have laid a solid foundation for the in-depth development and utilization of non-metallic minerals and provided technical support for the development and utilization of mineral resources in the direction of environmental friendliness and sustainable development. At present, more than 60 related academic papers have been published, and the results have been valued by colleagues at home and abroad.
Today, when human beings attach great importance to sustainable development, the comprehensive utilization of resources is a very important and urgent topic, involving many chemical, chemical and environmental problems in the processing and utilization of resources. On the basis of the existing work, this direction strives to develop into a research base for comprehensive utilization of nonmetallic minerals in Anhui Province during the Eleventh Five-Year Plan period, and is committed to strengthening the research and development of green processing technology and new application fields of mineral resources, so that the development and utilization of resources will develop in the direction of environmental friendliness and sustainable development. Separation engineering and technology is an important unit process of chemical engineering and technology, the core of downstream processing technology of chemical and biological engineering, and one of the hot research fields of international chemical industry. The separation and refining process plays an important role in many industrial fields, such as chemical engineering, fine chemical industry, agricultural product processing engineering, food engineering and so on. In-depth study on the separation and purification technology of chemical products and bioactive components is helpful to transform China's rich biological resources advantages into economic advantages in time, and has far-reaching significance to enhance international competitiveness and promote the scientific, rapid and sustainable development of related industries.
The research direction closely follows the forefront of international separation and refining engineering, focusing on industrial production processes such as chemical industry, petrochemical industry, light industry, pharmacy and biology. Focusing on new separation technologies and equipment such as membrane separation, complex extraction, supercritical extraction, rectification and adsorption separation, we will develop product molding spray drying, reaction separation integration process, new functional chemicals development, chemical process design and control, etc. In addition, many gratifying scientific research achievements have been made in chemical energy saving, heat exchange and environmental protection.
This direction has published more than one research paper 100 in famous academic journals at home and abroad, and won the national invention award and the national scientific and technological progress award 1, 6 provincial and ministerial awards and 4 utility model patents and invention patents. The research results have been widely used in many enterprises, such as the tail gas separation and recovery project of solvent factory, the membrane separation equipment of superfine powder production factory, the sharp-bend jet micro-powder classifier, the treatment of aminophenol production wastewater, the treatment of alkaline straw pulp papermaking black liquor by membrane method, the design of oxalic acid plant, the separation and purification of natural drugs and so on. This direction is engaged in the research and development of automobile and motor vehicle-related chemicals, involving the detection, analysis and evaluation of automobile plastics, automobile rubber, automobile water-based adhesives, automobile coatings and coatings, interior environment and automobile chemicals. The main research contents in this direction include:
Unification of automobile plastics: There are dozens of plastics used in automobiles, which brings greater difficulties to the recycling of materials, thus raising the issue of unification of automobile plastics. Modified polypropylene materials for automobiles can be divided into several categories, such as low temperature, high impact resistance, high rigidity, heat resistance and low warpage, so that more than 30 kinds of polypropylene materials for various automobiles can be unified as much as possible. Through the development of several large varieties, the development and recycling costs are reduced, which has good economic and social benefits.
Development of special material for automobile bumper: Automobile bumper is an important link in the process of automobile lightweight, which plays a role in beautifying the body and improving the driving safety factor. The new bumper special material requires lower cost, better performance and recyclability, which has made a small breakthrough in the development of color masterbatch.
Development of automobile dashboard skeleton and skin materials: distinguish different grades of vehicles and user needs, and develop high-quality automobile dashboard skeleton and skin materials for various needs. PC/ABS or PBT/ABS alloy materials can be used as the skeleton of high-end vehicles; PP skeleton material can be used for middle and low-grade cars, and hard PVC skeleton material can be used for low-grade cars. In the development of polyurethane for dashboard skin material, we have accumulated rich research experience, and cooperated with Hefei Amway Polyurethane Group to develop the production formula and technology of new polyurethane artificial leather material.
R&D of POM, PA engineering plastics and their * * * mixed modified products: We have done a lot of work in flame retardant modification and wear resistance of POM engineering plastics, published many academic papers, and had a pleasant cooperation with Hu Fei Automobile. He has rich experience in the development of nylon and glass fiber modified materials.
Coating system: The overall development idea is to develop into environment-friendly coatings on the premise of gradually improving performance. At present, the main research directions of other coatings are: water-based coatings; High solid paint; Ultra-high solid coating; Powder coating; Light-cured coating. As a part of fine chemical industry, coating additives play a very important role in the development of coatings. Combined with the development of coating special resin and coating system, coating additives were developed to form a complete system.
Detection, analysis and evaluation of interior environment: Various types of automobile interior materials are widely used, such as body materials, thermal insulation materials, engineering plastics, floor leather and adhesives. And dozens of polymer materials are used, all of which contain certain toxic and harmful substances. Successfully completed the project entrusted by Jianghuai Automobile, and took the lead in formulating the enterprise standard of air quality inside automobiles in China and passed the provincial appraisal. It has been in the forefront of China in carrying out environmental inspection, analysis and evaluation of automobile trunk, devoting itself to finding the pollution source of trunk and putting forward measures and countermeasures to control pollution source.