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Fudan scientists say artificial biological kidney will come out soon. Do you think there will be rejection between artificial kidney and human body?
I think there will be rejection between artificial kidney and human body, which is also a problem that needs to be solved in future medicine. Fudan scientists say that artificial kidney or kidney diseases will trouble many people, but limited by medical technology, many kidney diseases cannot be cured. According to the published data in the medical field, the normal human kidney is composed of retrorenal mesenchymal and ureteral teeth, and some institutions discovered how to make the first piece called retrorenal mesenchymal from human stem cells many years ago. A few days ago, an international research team composed of scientists from Sichuan University and Fudan University cultivated another kidney structure, namely ureteral bud.

It is understood that it can grow into an adult kidney collection system, and combined with previous research results, it is expected to cultivate a complete human biological kidney through Petri dishes in the future.

I think there will be rejection between artificial kidney and human body, which is a problem that needs to be solved in medical field. At the present stage of renal transplantation, the common problems are renal origin and rejection. There are acute rejection and chronic rejection, both of which will lead to the special physical condition of renal transplant recipients, while chronic rejection is even difficult to reverse, which may lead to the loss of transplanted renal function.

If scientists use artificial technology to make artificial kidneys, they can only solve the problem of kidney origin, but I think it will also produce rejection with the human body. Because even if the corresponding substances are obtained from the human body to cultivate artificial kidneys, it is difficult for medical technology to completely cultivate Petri dishes suitable for everyone's specific situation. It is very possible to cultivate in a unified environment, but this culture environment is bound to be very different from the internal environment of the human body.

This leads to a high probability of rejection after renal transplantation, which is also one of the difficulties that medical technology needs to overcome in the future.

In fact, the living and growing environment of organs in each human body is different. As long as an organ transplant is done, there is a high probability that rejection may occur. This is also a difficult problem to solve in medicine. It may take quite a long time to truly achieve a technological breakthrough and truly solve the rejection problem of organ transplantation.