? Baby allergic cough's asthma is over-treated, supplemented with anti-allergic probiotics, ignoring immune regulation and physical improvement. The health status of allergic baby is so worrying!

? Inhalation of glucocorticoids to treat respiratory variant asthma in allergic cough has become one of the most effective and popular methods to treat asthma in allergic cough. Although it is said that the side effects of Shunning are small, long-term use or inhalation of hormones can minimize the side effects of hormones, there are still risks in controlling asthma by repeatedly using antiallergic drugs or inhaling hormones for a long time, including hormone abuse and overdiagnosis of asthma.

Syndrome Differentiation and Allergy

? At present, domestic well-known pediatric respiratory experts point out that children with allergic asthma in allergic cough have problems of overdiagnosis and medical treatment, so everything is necessary. Long-term use of hormone inhalers or histamine receptor antagonists such as Shunning and Loratadine to antagonize histamine and leukotriene receptors will inevitably lead to other functional changes in the human body, and new intractable diseases will appear in the near future. It is urgent to supplement Kangminyuan anti-allergic probiotics to allergic babies to regulate immunity and improve allergic constitution.

? Children are prone to respiratory diseases when they are 2- 12 years old, which is related to their physical development. During this period, there will be repeated respiratory infections, airway hyperresponsiveness, variant asthma in allergic cough or children who have been diagnosed as allergic asthma. Is there really no other way except long-term inhalation of glucocorticoid and taking histamine receptor antagonists? Drugs play an important role in controlling the symptoms of allergic diseases or chronic airway inflammation, but at present, medical care has not given deep consideration to the airway repair of children with allergic rhinitis, cough and asthma, and no one has told young parents how to properly care for their children when they encounter allergic airway diseases.

? Non-drug intervention in asthma has attracted enough attention from experts at home and abroad. Drug or hormone therapy can not bring good prognosis to children with asthma. Intestinal flora is the foothold of early prevention of asthma. In the early stage of children's asthma or children's allergy, Kangminyuan anti-allergic probiotics with special effects can be given to complete this special immune function change against allergic reactions. Probiotics, as microorganisms, are distributed in all aspects of the human body, not only in the intestine, but also in the respiratory tract and skin. These flora are all involved in allergic asthma.

? Allergic rhinitis does not interfere with allergic immune regulation, and 60% of children with cough variant asthma will develop into allergic cough within two years. Children with cough variant asthma will develop allergic asthma after three years if they only use antiallergic drugs and do not interfere with allergic immune regulation. This can understand why children have been taking drugs in the treatment of allergic diseases, but they can't stop the development of allergic diseases and eventually develop into asthma. When we supplement Kangminyuan anti-allergic probiotics to children during medication, we can adjust the immune anti-allergy, change the prognosis of allergic cough's and cough variant asthma, greatly reduce the medication cycle and recurrence rate, and solve the recurrence problem of children in allergic cough after drug withdrawal in this way.

? Kangminyuan antiallergic probiotics mediate immunoglobulin IgE pathway, and improve airway hyperresponsiveness and lung function in children with allergic cough and asthma by repairing respiratory microecological flora. These functions are therapeutic functions that hormones and drugs cannot satisfy. Kangminyuan probiotics can greatly improve the recovery and prevention of allergic diseases in children such as eczema and urticaria in allergic cough, and establish microbial barrier function for children. This theory leads people to a new field of asthma pathogenesis and treatment, that is, intestinal microecology mediated IgE.

? The stable state of flora directly affects the course of allergic asthma, and long-term inhalation of hormones and antiallergic drugs can not affect the course and prognosis of asthma. Kangminyuan Probiotics, an antiallergic probiotic strain composition with special functions, has become a favorable scientific support for the new discovery of intestinal bacterial allergic diseases by reducing TH2 immune response caused by allergy, enhancing TH 1 immune function and regulating Treg immune cells. For children with allergic rhinitis, allergic cough's disease, cough variant asthma, allergic asthma and even asthma caused by asthmatic bronchitis and repeated respiratory infections, Kangminyuan can be supplemented as soon as possible to interfere with the IgE pathway mediated by intestinal microecology and inhibit the production of IgE allergic antibodies, thus improving the course and prognosis of allergic asthma in children and reducing the recurrence rate of asthma.

? Influenced by modern social environment and diet, allergic diseases are increasing. The research of microbial anthropology has found that there are countless microbial flora in various parts of human body, such as respiratory tract and skin, which play a role in balancing immunity and contribute to human health. The existence of some beneficial bacteria teaches our immune system which substances are good and which are bad. When allergies occur, the immune system has a wrong cognition. The main reason for treating good things as bad things is that there are too few beneficial bacteria to educate immune cognition in advance, which leads to self-harm. In the treatment of allergic diseases, we can supplement Kangminyuan's anti-allergic probiotics, regulate human flora from the microbial aspect, re-educate people's immune system, correct immune response, and solve allergic problems from another way.

The incidence of allergic diseases (allergic asthma, allergic cough's disease, cough variant asthma, allergic rhinitis complicated with allergic conjunctivitis and sinusitis, acute and chronic urticaria, atopic dermatitis and eczema) has soared, and adults and children are troubled by allergic diseases. At present, the routine treatment of allergic diseases is as follows:

(1) antihistamines: such as loratadine and cetirizine hydrochloride, and hormone inhalers commonly used for asthma in allergic cough, such as montelukast sodium and fluoxetine, have been used for a long time to treat asthma in allergic cough.

? Simple antihistamine or inhaled hormone atomization can relieve allergic symptoms in a short time, but the relief of allergic symptoms does not mean the disappearance of allergic diseases. Many allergic patients have a deep understanding of this. Repeated allergies and repeated medication seriously affect the quality of life, work and study. Children's allergic diseases are more harmful than adults. Infants' allergic constitution and allergic diseases are more likely to cause colds, repeated respiratory infections, repeated use of antibiotics and other diseases. Seriously affect the growth and development of children, and even let the whole family fall into an endless situation of repeated medical treatment and repeated allergies. Parents are even under great pressure to supplement Kangminyuan anti-allergic probiotics. The efficacy lies in solving immune overreaction, reducing serum IgE antibody, reducing TH2 immune response caused by allergic reaction, enhancing TH 1 immune function, regulating Treg immune cells, and enhancing immune antiallergic ability. Supplement Kangminyuan anti-allergic probiotics, reduce the drug use of children with variant asthma in allergic cough, shorten the drug treatment cycle of allergic children, and improve the recovery of variant asthma in allergic cough.

Imagine if a child with allergic rhinitis in allergic cough can get a comprehensive and perfect anti-allergic treatment plan and stick to anti-allergic adjustment. Although the allergy can't be cured, a large number of anti-allergic probiotics Kangminyuan can improve the allergic constitution, reduce the recurrence rate of allergies, shorten the medication cycle of children, and enable children with variant asthma in allergic cough to live and study like normal people, which is what doctors often say is the current clinical cure. At present, some top experts in children's respiratory diseases in China have clearly pointed out whether long-term inhalation of hormones to treat allergic cough and asthma will bring harm to children, and combined with the concept of "lung and large intestine are exterior and interior, treating lung first" mentioned by ancient Chinese medicine. Therefore, the international microbiology research "Application of Microbial Flora and Allergic Probiotics in Allergic Asthma" has solved the direction of immunomodulation and antiallergic treatment in respiratory allergic rhinitis, cough and asthma which are difficult to be solved by hormones and western medicine.

First, the treatment status of allergic asthma:

Environmental control means staying away from allergens, but for allergic asthma patients, not only are they affected by allergens, but also changes in temperature, air pressure and temperature can cause immune allergic reactions and induce or aggravate asthma. In addition, the increase of haze days leads to the deterioration of air quality. Therefore, it is not easy to stay away from allergens.

Although drug therapy can basically effectively treat and control allergic asthma, even long-term drug or hormone therapy can not change the natural process of allergic asthma development, and long-term drug control of asthma can not effectively prevent allergic asthma.

In addition to drugs, Lactobacillus salivarius PM-a 0006；; Add Kangminyuan patented strain of antiallergic probiotics to reduce IgE and regulate immunity. Lactobacillus Grignard PM-a 0006；; Lactobacillus yoelii PM-A0009 can reduce serum allergen-specific IgE antibody, and has preventive and therapeutic effects on allergic asthma. Many double-blind placebo-controlled clinical trials as evidence-based medicine have also confirmed that lowering serum IgE immunotherapy can indeed improve the symptoms and recurrence of allergic asthma, allergic rhinitis and conjunctivitis, shorten the period of drug or hormone therapy, and reduce the dosage of asthma patients (especially allergic asthma children). The immunotherapy effect of Kangminyuan anti-allergic probiotics in preventing and treating allergic asthma has been highly affirmed by experts at home and abroad, which fully shows the advantages of non-drug specific immunotherapy.

The most ideal treatment strategy for allergic asthma recommended by EAACI;

1. Early diagnosis and factors coexisting with bronchopneumonia should be made for the onset of allergic asthma in children, and early anti-inflammatory and antiallergic combined treatment scheme should be adopted;

2. Use the best drugs or hormones to control the symptoms of asthma attack;

3. Adopt the correct allergen diagnosis method to evaluate the degree of allergic reaction and the change of immune function;

4. Immunomodulatory therapy to change the development of allergic diseases, including immunotherapy to avoid contact with allergens and reduce IgE, reducing the allergic antibody IgE in vivo through Kangminyuan antiallergic probiotics, balancing the function of immune B cells, reducing the immune response of excessive TH2, inducing the correct immune response of dominant TH 1 type, and adjusting immune function to make the correct immune response to so-called allergens.

? By supplementing Kangminyuan, an antiallergic probiotic, the immunotherapy of IgE can be reduced, and the amount of drug treatment can be gradually reduced, so that the condition of allergic asthma patients can reach the best state of continuous and stable condition with the minimum dose or after stopping asthma antiallergic or even hormone control.

Second, anti-allergic probiotics Kangmin source reduces IgE and anti-allergy.

? The increase of serum IgE is the most powerful hint of allergic diseases. Allergens enter the body to induce specific IgE, which combines with mast cells and eosinophils to make the body enter a state of specific sensitization to allergens. When the allergen comes into contact again, it will combine with the IgE receptor on the cell membrane to cause a series of biochemical reactions, and then release various bioactive mediators related to allergic reactions and inflammation, such as histamine.

? Allergy is an immune disease, which is an imbalance of human immune function. Allergic patients often find that many allergic diseases can be seen in the same patient during clinical investigation. For example, allergic cough appears slowly after allergic rhinitis, and some children have urticaria or atopic dermatitis. Compared with normal people, the serum IgE of allergic patients increased significantly, mast cells increased and IgE receptors on cell membrane increased. Clinical medicine has proved that helper T cells and their cytokines play an important role in regulating the composition of IgE.

? According to the secretion of cytokines, helper cells are divided into two subgroups: TH 1 and TH2. Cytokines secreted by TH2 cells play an important role in antibody formation and allergic reaction. TH 1 and TH2 are regulated by cytokines. Under healthy conditions, TH 1 and TH2 are simultaneously balanced and regulated by helper T cells. When helper T cells lack regulatory ability or come into contact with some foreign proteins or small molecules (such as dust mites, pollen or seafood, etc.). ), TH2 is over-activated, which leads to the excessive secretion of TH2 cell hormones, leading to the increase of IgE and serum IgE concentration. To reduce IgE antibody, it is necessary to supplement Kangminyuan compound antiallergic probiotic strain to reduce serum IgE antibody.

Thirdly, reduce allergen-specific IgE.

? Anti-allergic Probiotics Kangminyuan Probiotics adopt physiologically acceptable probiotic ingredients with enhanced anti-allergic ability: Lactobacillus salivarius, Lactobacillus Grignard, Lactobacillus yoelii, Lactobacillus lactobacillus paracasei and Lactobacillus Roy. By promoting the secretion of interleukin 12(IL- 12) and interferon γ, allergic symptoms can be effectively improved, Th 1 type immune response can be regulated, and immunoglobulin IgE can be inhibited. Compound antiallergic probiotic strains bind to receptors on intestinal wall dendritic cells, activate the translation proteins in cells to move to the nucleus, and release a large number of cytokines, which is a link of innate immunity. Therefore, through its cell wall, diabetic substances such as peptidoglycan, lipopolysaccharide and polysaccharide can indeed activate the development of T cells through the innate immune system.

Four. IgE and allergic cough variant asthma in children.

? The increase of total IgE level and specific IgE level in the body is the common feature and common identification mark of atopic and allergic asthma, and the IgE level is positively correlated with the severity of allergic cough's disease and asthma. The increase of IgE level in the body can often reflect the allergic symptoms of allergic patients with persistent asthma in allergic cough. The research on a group of asthmatic children shows that IgE level is related to the diagnosis of asthma and AHR, and the increase of IgE has been identified as a risk factor for asthma, even in patients with non-allergic allergic asthma. Prospective studies have shown that exposure to allergens and subsequent IgE increase are related to the possibility of asthma in atopic families.

? Parents' genes will make children have atopic characteristics at birth. This congenital allergic constitution is a potential risk factor for children to suffer from allergic rhinitis and allergic asthma in later life. Under the influence of acquired environmental factors, these children are extremely susceptible, and respiratory infections and allergic reactions are easy to develop into allergic asthma. Most patients with allergic asthma have obvious family history and genetic history, especially children with asthma. The proportion of atopy in children with asthma is significantly higher than that in normal children, which is mainly manifested in the obvious increase of serum total IgE and specific IgE levels, the increased prevalence of eczema in infants and young children, and the increased incidence of allergic diseases such as allergic rhinitis and urticaria.