973 subproject1;
Large aircraft project 1. 9 items, 6 items (including major 1 item), 15 items, 20 10 items, 6 items, 1 item (including major1item), 5 items and 20/item.
Ministry of Science and Technology 1 International Exchange Program. 15, 10 (including 2 major items), and 8 instruments and equipment.
Thermal analyzer, ultraviolet-visible spectrophotometer, atomic absorption spectrophotometer, element analyzer, fluorescence spectrometer, high performance liquid chromatograph, gas chromatograph-mass spectrometer, gas chromatograph, ion chromatograph, Fourier transform infrared spectrometer, X-ray powder diffractometer, inductively coupled plasma emission spectrometer.
Books and reference materials
The reference room of the Department of Materials and Chemistry and Chemical Engineering of Suzhou University currently covers an area of about 300 square meters and is a professional reference room providing services for teachers and students in the department. The readers are teachers, graduate students, senior students and literature students. It mainly collects Chinese and foreign periodicals, reference books and reference books related to chemistry and chemical engineering. American chemical abstracts C.A. (including abstracts, volume indexes, cumulative indexes, etc. ) from the first issue 1907. At least 1 1 publications were collected before 1930' s, and have been continuously collected up to now. Such as Journal of American Chemical Society, Journal of Chemical Society, Chemical Review, Journal of Chemical Education, Journal of Physical Chemistry (Physical Chemistry), Journal of Organic Chemistry (Organic Chemistry), Journal of Electrochemistry (Electrochemistry), etc., and also collected Gmelim (Encyclopedia of Inorganic Chemistry) and Beilstein'. In 20 12 years, the collection of bound periodicals in the reference room of the School of Chemistry and Chemical Engineering has reached more than 30,000 volumes. There are more than 250 kinds of periodicals, with more than 4000 volumes of periodical binding/kloc-0. Collection of books 13000 volumes. Professor Lu Xiyan, academician of China Academy of Sciences and Shanghai Institute of Organic Chemistry, donated 2,500 famous periodicals and reference books to the reference room. The reference room has gradually formed a professional collection system with key disciplines and key laboratory documents as the core and materials and chemistry as the research-level characteristics. At the same time, the reference room has also set up a 50-square-meter electronic reading room, equipped with more than 20 computers, providing computer access and document retrieval services, and often providing retrieval services for teachers and students, brother colleges and industrial and mining enterprises. The following are ten latest academic papers (as of March, 2065438 1): The research group of Professor Dai Jie and Professor Zhu Qinyu published the research paper 20 13-02-20 on CrystEngComm, and reported that a series of coordination polymers were obtained with TTF tetracarboxylic acid as ligand under different coordination modes. The factors affecting the polymer structure are discussed. The complexes obtained at room temperature are all one-dimensional, while the coordination polymers obtained at solvothermal conditions are two-dimensional and three-dimensional. These coordination polymers can be oxidized in solid state to obtain positive monovalent radical cations and positive divalent cations. The research group of Professor Dai Jie and Professor Zhu Qinyu published the research paper 20 13-02-20 on phys.chem, and studied the redox acid-base system formed by tetrathiafulvalene (TTF) dicarboxylic acid and nitrogen-containing heterocyclic compounds. Both NMR and crystal structure show that there are proton transfer and strong hydrogen bonds between TTF dicarboxylic acid and nitrogen-containing heterocyclic compounds. Different from monocarboxylic acid system, TTF dicarboxylic acid can easily transfer one proton to alkali, and then the second proton forms a stable seven-membered ring. The electrochemical results show that the mechanism is a two-step tetragonal redox and proton transfer mechanism. The research group of Professor Dai Jie and Professor Zhu Qinyu published the research paper 20 13-02-20 in Inorg. Chemistry. Solvothermal synthesis of oxygen clusters containing six titanium atoms is reported. In addition to alkoxide, dicarboxylic acid ligands were introduced for the first time and their crystals were cultured to obtain crystal structure data. This is a rare titanium oxide cluster with single crystal photochromic effect. Illumination transforms Ti(IV) into Ti(III), and oxygen molecules are transformed into oxygen free radicals after contact with air, which is confirmed by ESR measurement. The photolysis of the compounds was also studied. The research group of Professor Dai Jie and Professor Zhu Qinyu published the research paper 20 13-02-20 in J. phys.chem. The response of tetrathiafulvalene (TTF) carboxylic acid system (DMT-TTFCOOH) to pyridine containing nitrogen was also studied. The selectivity of the response was discussed by NMR and cyclic voltammetry, and the electrochemical response mechanism was proposed. Through theoretical calculation and crystal structure determination, the types and strengths of intermolecular hydrogen bonds and their important role in molecular response are analyzed. The system is a unique hydrogen bond response system with redox activity. Professor Ni Peihong's research group published the research paper 20 12- 12-25 in Polymer magazine. The synthesis and characterization of amphiphilic block copolymer PCL-b-POPEA with acryloyloxy groups on its side groups are reported. This kind of block copolymer has good biocompatibility and complete biodegradability. In this study, the carbon-carbon double bond (C=C) was introduced into the side group of amphiphilic polyphosphate block copolymer for the first time, which can react with mercapto (-SH)-containing organic compounds by Michael addition reaction. The modified polyphosphate has functional groups, such as -OH, -COOH, -NH2, amino acids, etc. The copolymer PCL-b-POPEA self-assembled in water to form nano-micelles with hydrophobic segment PCL as the core and hydrophilic segment POPEA as the shell. Because of its good biocompatibility and biodegradability, the micelles can be further used as drug carriers to deliver adriamycin, and release adriamycin more quickly and effectively under the action of phosphodiesterase I. At the same time, the drug-loaded micelles of these polymers can significantly inhibit the proliferation of human nasopharyngeal carcinoma cells (KB cells). Professor Ni Peihong's research group published a research paper 20 12- 12-25 in Langmuir magazine. In this paper, magnetic nanoparticles modified by polycation containing cholesterol were designed and synthesized, which were used to condense DNA to obtain magnetic cation carriers. Combining the advantages of brush copolymer, such as biocompatibility, anticoagulation and protein adsorption resistance, a brush polyanion containing sulfhydryl group (-SH) was prepared. Through electrostatic action, as an anionic layer with hydrophilic and nonspecific adsorption resistance, sulfhydryl (-SH) is crosslinked to form disulfide bonds (S-S) under the action of H2O2 or O2, which can improve the stability of the carrier in the blood circulation process. In the simulated cell environment, the cross-linked disulfide bond (S-S) breaks, releasing the wrapped DNA. The experimental results show that the self-assembled gene vector has magnetic response, cell reduction sensitivity, protein adsorption resistance and low toxicity, and can be effectively transfected into HEK293T and HeLa cells, which has potential application value. Professor Ni Peihong's research group published the research paper 20 12- 12-25 in Soft Matter. In this paper, a kind of polyphosphate macromolecular crosslinking agent with double bonds at both ends was prepared by combining ring-opening polymerization with hydroxyl esterification at the end of polymer. By mixing it with the aqueous solution of cationic monomer 2- dimethylaminoethyl methacrylate and initiator ammonium persulfate, hydrogel can be quickly formed at room temperature without adding any accelerator. The sol-gel transition process was studied by rotary rheometer, and the factors affecting gelation time were further investigated. It is found that the gelation time can be adjusted by changing the ratio of reactants. The swelling behavior, pH response, internal porous structure and cytotoxicity in vitro of the hydrogel were studied, and the drug release performance of the injectable hydrogel in vitro was studied with adriamycin hydrochloride as a model drug. The results show that this kind of hydrogel has good cell compatibility, can quickly form drug-loaded gel at room temperature, and has potential application prospects in drug controlled release. Professor Ni Peihong's research group published the research paper 20 12- 12-25 in J. Polym. Sci。 Part a: polymer. Chemistry. In this paper, a controllable magnetic targeting gene vector with Fe3O4 magnetic nanoparticles as the core and PEG as the crown was prepared by layer-by-layer assembly and shell crosslinking. Poly (2- dimethylaminoethyl methacrylate) (PDMAEMA) was grafted onto the surface of magnetic nanoparticles by free radical polymerization, and then assembled with DNA, homopolymer PDMAEMA and polyanion MePEG2000-b-PMAASH containing partial sulfhydryl groups by electrostatic interaction, thus obtaining a compound gene vector with water-soluble PEG chain on the surface and diplomatic connection. Gel block electrophoresis and zeta potential test tracked the process of layer-by-layer assembly. The experimental results show that the composite nanoparticles have low toxicity and stability of simulating in vivo circulation conditions, and can be used as potential non-viral gene carriers.
Oxidative dehydrogenation coupling reaction has the characteristics of atomic economy, low energy consumption and environmental protection. At the same time, it is also a simple and efficient method to construct complex bioactive drug molecules and natural products. The oxidative dehydrogenation coupling reaction of copper and oxygen has attracted extensive attention of organic workers because of its high efficiency, low cost and easy control, and has been deeply studied. In this paper, the aerobic oxidation of copper and its regularity are reported: 1 equivalent acetophenone and 3 equivalent benzylamine can easily and efficiently synthesize polysubstituted imidazole compounds in the atmosphere of 20 mol% cuprous iodide, 10 mol% boron trifluoride ether and oxygen; The functionalization of SP C-H bond was realized, and the elimination of 8 hydrogen atoms and the formation of 3 new C-N bonds were realized in one step. The only by-product of the reaction was green, nontoxic and harmless water.
Professor Ji Shunjun's research group published research paper 2012-12-10 in Organic Express (if: 5.862).
In this paper, a multi-component insertion reaction involving acenaphthene quinone was reported, and a series of multi-substituted pyrazolo isoquinoline skeleton derivatives were synthesized conveniently and effectively. In this reaction, two C-C bonds were broken by one-step activation, and the active methylene of dibenzoyl methane was inserted between two sp-spC-C bonds of acenaphthene, thus realizing the C-C bond insertion reaction catalyzed by metal-free reagents, and at the same time constructing two new 6 yuan rings.