Ephedrine and pseudoephedrine cannot react with a large number of alkaloid precipitation reagents, but the following two characteristic reactions can be used to distinguish ephedrine from pseudoephedrine.

1. Carbon disulfide reacts with copper sulfate to produce brown precipitate of ephedrine and pseudoephedrine, which belongs to secondary amine. Methylephedrine is a tertiary amine, and protomethyl pseudoephedrine comes from the medical education network and does not react with desmethylephedrine and desmethyl pseudoephedrine from primary amine.

2. Copper double salt reaction Adding copper sulfate and sodium hydroxide to the aqueous solution of ephedrine and pseudoephedrine, the solution was originally created by Lanzi Medical Education Network.

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