Chongqing Second Foreign Language School was formerly known as Chongqing Girls' Middle School founded by 1940. 1952, under the personal care of Duncan, director of Chongqing Education Bureau, she moved from Tan Xuan Temple to Tushan Lake and was renamed Chongqing No.4 Girls' Middle School. 1969, renamed Chongqing No.4 Middle School. 1997, with the approval of Chongqing Municipal People's Government, was transformed into Chongqing Second Foreign Language School, becoming a joint-stock, full-time and fully enclosed middle school, and the only joint-stock municipal key middle school in Chongqing.

Chongqing International Studies University is a school with its own characteristics, and its foreign language characteristics are its most prominent and fundamental characteristics. The school puts foreign language teaching in a prominent position, and employs foreign language professors and foreign teachers from Sichuan International Studies University to give teaching guidance to English teachers in the school all the year round. For non-graduate students, 7 regular classes are arranged every week, 1 foreign teacher class, 3 morning reading classes and 4 evening listening classes.