1993.9~ 1998.7 Bachelor of Clinical Medicine, Taishan Medical College1998.9 ~ 20010.7 Master of Physiology, Tongji Medical College, Huazhong University of Science and Technology 2005.9 ~ 2008./kloc-0.2 Doctor of Pharmacology, School of Medicine, Shandong University: 200/2. From March 2007 to September 2008, he was sent to the Department of Neurology, Emory University Medical College for cooperative research abroad. 2011.1~ 2012 was sent to the Department of Neurology, Emory University School of Medicine, USA for cooperative research. Award 1. 20 10 excellent doctoral dissertation of Shandong university 20 10B022 2. 20 10 first prize of the 2nd Shandong Pharmacology Society-Freda Young Pharmacologist Award 3. 20 1 1 Shandong natural science award (third prize) 5 major scientific research projects 60. Effect and mechanism of tPA preconditioning on neuronal apoptosis induced by cell cycle recurrence: Research on the role and mechanism of National Natural Fund of China 600,000 2065,438+0 ~ 2065,438+05.12 An Jiezhang Chen Hongyan Lin Weichun Min He Min 2. tPA and LRP 1 of neurovascular units in ischemic brain tissue. 2 10/0,000 2010.1~ 2012 An Huiqing Zhang Sun Wang Xiuling 3. ang Ⅱ-ATR-LRP1Signal Pathway's Role and Mechanism in the Formation of Ischemic Brain Edema: Shandong Outstanding Young and Middle-aged Scientists Research Award Fund 20655. +0base270536000 2011.7-2014.7 Study on the Protective Effect and Mechanism of Xiumei An Wei Zhangsun No.4. TIPE No.2 on Cerebral Ischemia-Reperfusion Injury National Natural Fund (Youth Fund) 6438+080000 20688+000.500001.00000000006 2 An Ziying, Zhang Qiu, Chen, Chen Xiuling and Yanqing 5 .COX-2/mPGES- 1/PGE2 Pathway Study on the Role and Mechanism of NOD2 in Cerebral Ischemia-reperfusion: Shandong Outstanding Young and Middle-aged Scientists Research Award Fund 62,065,438+00-2065,438+03 Emily Liu, Zhang Xiumei, Zhang Xiumei. Zhang Bin, Chen Lin, and 6 items. Effects of acetyl puerarin on apoptosis induced by TLR9 in cerebral ischemia-reperfusion injury and its mechanism: PI3K/Akt/GSK mediated by ZR2010HM1325000+01-2012, Chen Lin, Wei and Xiang 7 .7. The Role of TLR9 in Apoptosis Induced by Cerebral Ischemia/Reperfusion Injury: The Doctoral Program Special Research Fund of the Ministry of Education 2.01E+1336000+01-2013 Chen Lin, Zhang Xiumei, Yu Sun 8. Study on the role and mechanism of catenin p 120 in the formation and development of atherosclerosis: Talent Introduction and Training Class of Shandong University Independent Innovation Fund 2010GN0386000 2010.12012 Yu Sun, Zhang Xiumei. Yang Jianmin 9. The role of SP- 1 and Toll-like receptor pathways in cerebral ischemia and the mechanism of HDAC inhibitors 2009GG 100203 1 Shandong Science and Technology Development Plan in 20091200002009.8-201. Zhang yanying 'an street 10. Study on the role and mechanism of histone deacetylase inhibitor in cerebral ischemia injury. In 2009, Shandong Excellent Young and Middle-aged Scientists Research Award Fund Plan BS 2009 SW 0430000 2009.12-2012, Wei, An Jie, Wang. Du bibliography 1. An Jie, deputy editor of Zhang Xiumei, edited by People's Military Medical Publishing House, No.2, 2006. Tongji University Press, edited by Zhang Xiumei and An Jie, Tongji University Press, March 2005. Zhang Xiumei, An Jie and Liu Yue 'e, multiple-choice questions in pharmacological reviews. Shanghai: Second Military Medical University Press, April 2004. Zhang Xiumei, editor of Anjie.