The significance of college students' safety education lies in improving their safety awareness and self-protection ability, creating a safe and civilized campus, and promoting their healthy growth and overall success. College students are a relatively high-quality group, but most of them are only children. They have a superior living environment since childhood, are used to relying on their parents, and have poor self-care and self-reliance ability. Most of them are confident in themselves, and their safety awareness and ability to withstand setbacks are not strong, which is easy to cause suicide, crime and loss of life and property. Therefore, it is of great practical significance to strengthen college students' safety education, which is not only the need for students to grow up, but also the need for the safe development of colleges and universities and the inevitable requirement for building a harmonious society.