Shanghai Civil Defence Science Education Museum is divided into four parts: Preface Museum, Civil Defence Museum, Disaster Prevention and Mitigation Museum and Retrospect and Prospect Museum. By showing historical air strikes, air strike weapons, modern air strike characteristics, etc. This paper mainly introduces the relevant knowledge and skills of civil air defense and various effective ways and means to deal with modern air strikes. Combined with the disaster-prone situation in Shanghai, the causes, hazards and protective measures of disasters such as typhoon, storm surge, lightning, earthquake, tornado, fire, chemical accident and infectious disease are emphatically introduced, and some interactive equipment and devices such as 4D cinema, subway escape and on-site rescue are used to let tourists experience and participate personally, and familiarize themselves with escape methods and self-help and mutual rescue skills.