The school's predecessor was Xikang Health Technology School, which was founded in March of 195 1. 1962 was renamed Sichuan Ya 'an Health School; In 2000, Ya 'an Education College, the predecessor of the college, merged Ya 'an Finance and Trade School, Ya 'an Agricultural Mechanization School and Ya 'an Industrial Bureau Technical School to form a new Ya 'an Education College. In April 2002, Ya 'an College of Education and Sichuan Ya 'an Health School merged to form Ya 'an Vocational and Technical College.
As of April 2023, the college has three campuses, namely Economic Development Zone Campus, Qingnian Road Campus and Yucai Road Campus, covering an area of more than 830 mu. Set up 50 majors in 9 secondary colleges in higher vocational colleges; Students18,800. By April, 2023, the college had established the second-level colleges of Marxism, Clinical Medical College (affiliated hospital), Nursing College, Pharmacy and Laboratory College, Traditional Chinese Medicine and Rehabilitation College, Basic Medical College, Intelligent Manufacturing and Information Engineering College, Normal College and Economic Management College, and 50 higher vocational majors.