Puffer is an incorrect name. Pufferfish is a mammal, and what you are talking about should be a general term for pufferfish. There are many toxins in the liver, blood and testis of wild river bream, especially in testis. Tetrodotoxin is a neurotoxin, which can be fatal in small doses. Since ancient times, people in China, Japan and Korea have been eager for the delicacy of river crabs, and they are not even afraid of its poison. Every year in Japan, diners are poisoned by eating river crab sashimi due to improper handling. With the deterioration of water quality in the Yangtze River basin and estuaries, strictly speaking, wild river bream is not easy to see. What is seen in the market now are cultured river bream, especially the series of river bream products in Hai 'an, Jiangsu. Zhongyanghe anchovy has a patent for non-toxic culture, and 500 million people can safely eat it. It can be said that it is a truly nontoxic fugu (puffer fish).