Usually this question is asked by girls. If boys ask, you can't get girls playing guitar. Guitar, a musical instrument, or most musical instruments, can actually be played by human beings, and the physiological gap will not be too big. It doesn't matter whether the hand is big or small, long or short, young or old. The most important thing is the correct hand shape, the flexibility of fingers and the extension and flexibility of fingers brought about by correct practice. At least in playing and singing, most songs in history will not be affected by physiology.