20 18 "primary pharmacist" examination questions and answers (5)
Type a problem
1. When purine nucleotide is synthesized de novo, it is first produced as follows:
A. Good operating practices
B. Ampere
C. international competition points
D. adenosine triphosphate
E.GTP
2. The final product of purine nucleotide decomposition in human body is:
A. Urea
B. creatine
C. creatinine
D. uric acid
E. β -alanine
3. The substances most directly related to nucleotide synthesis and sugar metabolism are:
A. Glucose
B.6 glucose phosphate
C. 1 glucose phosphate
D. 1, 6 glucose diphosphate
E.5 glucose phosphate
4. In vivo deoxynucleotides are directly reduced by which of the following substances?
A. ribose
B. nucleosides
C. nucleoside monophosphate
D. nucleoside diphosphate
E. nucleoside triphosphate
5.HGPRT (hypoxanthine-guanine phosphoribosyltransferase) participates in which of the following reactions:
A. de novo synthesis of purine nucleotides
B. de novo synthesis of pyrimidine nucleotides
C. remedial synthesis of purine nucleotides
D. remedial synthesis of pyrimidine nucleotides
E. purine nucleotide catabolism
6. The principle of fluorouracil (5Fu) in the treatment of tumor is:
A. the direct killing effect itself
B. inhibition of cytosine synthesis
C. inhibition of uracil synthesis
D. inhibiting thymidylate synthesis
E. inhibiting the synthesis of tetrahydrofolate
7. Amino acids providing purine rings synthesized by all N and C atoms in the molecule are:
A. serine
B. aspartic acid
C. glycine
D. alanine
E. glutamic acid
8. When purine nucleotides are synthesized de novo, the C-2 amino group of GMP comes from:
A. glutamine
B. asparagine
C. aspartic acid
D. glycine
E. alanine
9.9. The direct precursors of DTMP synthesis are:
A. Dump
B. trimethoprim
C. torsade de pointes ventricular tachycardia
Dudep
E.dCMP
10. The nucleotides that can be decomposed into β -aminobutyric acid in vivo are:
A. Corrugated Metal Pipe
B. Ampere
C. trimethoprim
D. referee
E. international competition points
1 1. What fragments of nucleic acid metabolism cannot be blocked by using glutamine analogues as antimetabolites?
Generation of A.A.IMP
B.XMP→GMP
C.UMP→CMP
D.UMP→dTMP
E.UTP→CTP
Answer:
1.C 2。 D 3。 E 4。 D 5。 C 6。 D
7.C 8。 A nine. A 10。 C 1 1。 A