For external hemorrhoids, drugs should be directly applied to the anus. For internal hemorrhoids, the medicine should be applied with the aid of a syringe, and the syringe should be inserted into the anus to squeeze out a proper amount of medicine. For mixed hemorrhoids, the medicine should be sent into the anus first, and then applied outside the anus, usually once in the morning and once in the evening, and the frequency of use can be increased according to individual circumstances.