What a pity that the discoverer of restriction endonuclease didn't win the prize! Because restriction endonucleases have changed the course of molecular biology, but deletion is deletion. Who can save it?

Now gene editing is just around the corner, which makes it so simple for human beings to manipulate genes, and also brings endless room for imagination, which can treat hereditary diseases, various chronic diseases and even tumors.

Although this technology is very young, it has shown great potential and space. Besides, why must the winner be the old man? When iPS won the prize, it was only a few years away from iPS! So gene editing has great potential.

2 tumor immunotherapy

Tumor immunotherapy was proposed 50 years ago, but it soon fell through, because simply "improving" immunity does not seem to be able to fight tumors. Only by violently slashing the tumor (chemotherapy, radiotherapy) is it reliable. Then, with the passage of time, breakthroughs in tumor immune mechanisms such as CTLA-4, PD- 1 and PD-L 1 have brought epoch-making changes to the treatment of tumors. In addition, the emergence of Car-T technology has also brought unprecedented progress to tumor cell immunotherapy!

Although tumor immunotherapy is still limited to some tumors such as malignant melanoma and hematological tumors, it may be effective for all solid tumors with technological breakthroughs in the future.

There is no reason why this technology should not win the prize. Even if you don't win this year, it's possible in a few years!

3 cell autophagy

Needless to say, the thermal field, we all know that there are many ways of cell death!

4 nuclear magnetic resonance technology

In recent 10 years, nuclear magnetic technology has advanced by leaps and bounds, which has brought great changes to medicine. Especially high-resolution magnetic resonance imaging technology, but will it really win the prize?