Why is Gu called Grandpa Sugar Pill?
Gu engaged in the research of live attenuated polio vaccine, established the method of isolation and finalization of polio virus, and formulated the trial production and safety standards of live polio vaccine. He presided over the formulation of China's first "Rules for the Production and Verification of Live Polio Vaccines", which guided the production and identification of billions of vaccines in China for more than 20 years.
During the period of 1957, the virus was isolated from monkey kidney tissue culture for the first time, and the epidemic of type I polio was confirmed by etiology and serology. From 65438 to 0958, poliovirus was isolated from the feces of nursing patients and successfully finalized, which provided a scientific basis for the formulation of immunization plan.
At the end of 1959, the country adopted Gu's suggestion, and the research of live polio vaccine in China started. From 65438 to 0960, Gu led a team to develop a live polio vaccine through animal and human experiments. Signing Ceremony of Confirmation Report on Polio Eradication in China 198 1 From then on, Gu began to study hybridoma technology with monoclonal antibody against poliovirus.
1982, Gu successfully developed the "polio" monoclonal antibody kit, successfully carried out the hybridoma technology of "polio" virus monoclonal antibody, and established three serotypes and a set of "polio" monoclonal antibodies. In 2000, the signing ceremony of the confirmation report on polio eradication in China was held in the Ministry of Health.