Black Ugliness: It means that the black morning glory is an annual twining herb with hairy plants. Leaves alternate, broadly ovoid or suborbicular, usually 3-lobed, apex lobes oblong or ovoid, lateral lobes short, triangular and pilose. Flowering in autumn, axillary inflorescence ... [taste of nature and taste]: bitter, cold. Toxic. Enter lung, kidney and large intestine meridian. [Efficacy]: Purging water to relieve constipation, killing insects and attacking accumulation. Indications: edema, loose stool, phlegm retention, asthma and cough due to adverse qi movement, and abdominal pain due to insect accumulation. [Usage]: decocted, 3-9g. Take the pills in powder, each time 1.5 ~ 3g. The medicinal properties of the product are slowed down. [Taboo]: It is forbidden for pregnant women. Not applicable to croton.
Pharmacological effects of white ugliness and black ugliness;
The chemical properties of morning glory glycoside are similar to Jalapin, which has a strong purgative effect. Petunia glycoside is decomposed into Petunia when it meets bile and intestinal juice in the intestine, which stimulates the intestine, promotes peristalsis and leads to diarrhea. According to animal experiments, diarrhea has no distinction between black ugliness and white ugliness. There is little research on the diarrhea principle of morning glory, which is different from magnesium sulfate and rhubarb. When it is excreted, it will not cause drastic changes in blood sugar, but it can accelerate the excretion of inulin in the kidney, which may have diuretic effect. The water extract and alcohol extract of morning glory have laxative effect on mice, but they lose their effect after decoction. The aqueous solution after the removal of morning glory glycoside still seems to have purgative effect, so it may contain other purgative components besides the known morning glory glycoside. In vitro experiments show that black ugly and white ugly still have certain insect repellent effect on boa constrictors. Morning glory glycoside seems to excite isolated rabbit intestine and isolated rat uterus; Intravenous injection 1mg/kg has no obvious effect on blood pressure and respiration in anesthetized dogs and rabbits. The lethal dose of subcutaneous injection to mice was 37; 5 mg/kg. Toxic to people, but not too much. In addition to directly stimulating the gastrointestinal tract, it may also cause vomiting, abdominal pain, diarrhea and mucus and bloody stools, and may also stimulate the kidneys and cause hematuria. Severe cases may damage the nervous system, leading to language disorders and coma. Ipomoeatricolor contains isoergotamine, ergotamine and naked ergotamine, which has magical effects. Diarrhea: 1.5-3g/kg seed ethanol or water extract can cause diarrhea in mice, but the decoction loses its diarrhea-causing ability. Exciting smooth muscle: 0.2% resin content has exciting effect on isolated intestine and uterus of rabbits; The lethal dose of subcutaneous injection in mice was 37.5 mg/kg. The salt of morning glory glycoside hydrolysate can make the small intestine, cecum and large intestine contract in guinea pigs, but morning glory glycoside itself has no such effect.