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Nature leads! Article Inventory of High and Middle Score Projects in 2022
Time flies, and in a blink of an eye, the process of 2022 is already over half. Despite repeated outbreaks, the scientific field is still developing vigorously and has made remarkable achievements. Many research results related to protein's omics and metabonomics were published in various sci journals with high scores, which constantly promoted the vigorous development of life science and precision medicine.

Zhongke New Life has been deeply involved in the application and development of protein's omics, metabonomics and other omics, and it is a great honor to participate in many scientific research work of omics research. According to incomplete statistics, in the first half of 2022, the client of Zhongke New Life published 2 1 1 omics articles, including Nature, Signal Transformation and Targeted Therapy, Natural Communication, Journal of Clinical Investigation, Advanced Science, etc., and 3 articles scored above 10. Cumulative impact factor 144 1.95, with an average impact factor of 7.39, which is fruitful!

Next, follow me to take stock of the high-scoring articles in the first half of 2022. While congratulating these scientific research teams, I also hope to provide some ideas and help for teachers' future scientific research plans.

0 1 protein page

# 0 1

File name: NLRs

Immunity triggered by coordinating patterns and effectors to defend metabolism.

Published periodical: Nature (if = 69.504)

Collaborator: Center for Excellence and Innovation of Molecular Plant Science, China Academy of Sciences.

The Service Content of Zhongke New Life: A Study of protein Group

# 02

File name: file

Eph receptor A4 plays a role in demyelination and depression-related behaviors.

Published periodical: Journal of Clinical Medicine

Investigation (IF= 19.456)

Partner: Mental Health Center affiliated to Shanghai Jiaotong University School of Medicine.

The Service Content of Zhongke New Life: A Study of protein Group

# 03

File name: HTR 1A

Suppress the development of triple negative breast cancer by the following ways

TGFβ? Normative and non-normative approaches

Published periodical: Advanced Science (if = 17.5438+0)

Partner: Cancer Hospital affiliated to Fudan University.

The service content provided by Zhongke New Life: protein appraisal of adhesive tape.

# 04

File name: CD73

Extracellular vesicles derived from HNSCC are defined as tumor-associated

Immunosuppression mediated by macrophages in microenvironment

Published periodical: Extracellular Journal

Vesicle] (IF= 17.337)

Partner: Shanghai Ninth People's Hospital

The service content provided by Zhongke New Life: an analysis of protein shotgun

# 05

File name: peroxidase

Millet bran exerts its anti-colorectal cancer activity through targeting.

Inactivation of STAT3 pathway by GRP78 on cell surface

Published periodical: Journal of Pharmacy

China B (if =14.903)

Partner: School of Life Sciences, Shanxi University

Services provided by Zhongke New Life: protein Appraisal.

# 06

File name: file

Potential role of rice cytoplasmic membrane proteins in response to zinc stress

Roots based on iTRAQ and PRM under low Cd conditions

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Partner: China Rice Research Institute.

Service content provided by Zhongke New Life: protein Quantitative (iTRAQ)

# 07

File name: Exogenous

Melatonin reduces NO2 damage in tobacco leaves by promoting antioxidation.

Defense, regulation of redox homeostasis and signal transduction

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Partner: College of Life Sciences, Northeast Forestry University.

The Service Content of Zhongke New Life: A Study of protein Group

# 08

File Name: Quantitative

Protein's omics and protein phosphate's omics clarified that.

Nanostructured titanium dioxide stimulates biofilm formation.

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Partner: School of Environment and Resources, Xiangtan University

The service content provided by Zhongke New Life: protein Genomics+Phosphorylated protein Genomics.

# 09

File name: Toxicology

Effect of tri (1, 3- dichloro -2- propyl) phosphate on oyster.

Protein group and protein phosphate group were used for analysis.

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Partner: Key Laboratory of Coastal Environmental Process and Ecological Restoration, China Academy of Sciences.

The service content provided by Zhongke New Life: protein Genomics+Phosphorylated protein Genomics.

# 10

File name: Fine tuning

Salicylic acid regulates drought tolerance of apples.

Publication of the periodical Plant Biotechnology

Log (IF= 13.263)

Partner: State Key Laboratory of Crop Stress Biology in Arid Areas (Northwest A&F University)

The Service Content of Zhongke New Life: A Study of protein Group

# 1 1

File name: phospholipase

A2 inhibitor and protein PINLYP containing LY6/PLAUR domain regulate type I.

Interferon innate immunity

Published periodical: PNAS (if = 12.78)

Partner: Key Laboratory of Molecular Virology and Immunology, Shanghai Pasteur Institute, China Academy of Sciences.

The Service Content of Zhongke New Life: A Study of protein Group

# 12

File name: Overexpression

Integrin α2 inhibits the activation of transforming growth factor β.

Pathway through TFCP2-SMAD2 axis in pancreatic cancer

Published periodicals: Journal of Experiment and Science; Clinical cancer research (IF= 12.658)

Partner: Union Medical College Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology.

The service content provided by Zhongke New Life: protein Mass Spectrometry.

# 13

File name: a? Rolstonia

Ralstonia solanacearum Effectors target TGA transcription factors to subvert

Salicylic acid signal

Published Journal: Plant Cell (if = 12.085)

Collaborator: Huazhong Agricultural University College of Plant Science and Technology

Services provided by Zhongke New Life: protein Appraisal.

# 14

Document Name: No.

Promoting autophagy initiation by targeting SCFβ-TrCP2 complex

Published periodicals: Cell Death &;

Differential "(IF= 12.067)

Partner: Department of Nephrology, Southern Hospital of Southern Medical University.

The Service Content of Zhongke New Life: A Study of protein Group

# 15

File name: O-glcn acylation

The stability of SIRT7 promotes the development of pancreatic cancer by blocking the growth of pancreatic cancer cells.

SIRT7-REGγ interaction

Published periodicals: Cell Death &;

Differential "(IF= 12.067)

Partner: The Second Affiliated Hospital of Zhejiang University School of Medicine

Services provided by Zhongke New Life: O-GlcNAc glycosylation modification.

# 16

File name: An

The unexpected role of BAG3 in regulating PARP 1 ubiquitination in oxidative stress

Stress-related endothelial injury

Published journal: redox biology (if = 10.787)

Partner: Institute of Health Sciences, China Medical University.

The Service Content of Zhongke New Life: A Study of protein Group

# 17

File name: An

The comprehensive multi-group method reveals the regulatory effect of melatonin.

Age-dependent mitochondrial dysfunction and lipid homeostasis in mice

hippocampus japonicus

Published Journal: Pharmaceutical Research (if = 10.334)

Partner: School of Life Science and Biopharmaceutical, Shenyang Pharmaceutical University.

Services provided by Zhongke New Life: A Study of DIA protein Group.

02 metabolism and lipids

# 0 1

File name: thrombin

ACSL4-dependent iron ptosis was induced during cerebral ischemia/reperfusion.

Published periodical: Signal Transduction and Targeting

Therapy (IF=38. 104)

Partner: Huaxi Hospital.

The service content provided by Zhongke New Life: Lipomics.

# 02

File Name: Machinery

Promoting the hydrolysis mediated by dimethylarginine dimethylamine hydrolase 1

Metabolite asymmetric dimethylarginine promotes bone formation.

Published periodical: Nature Newsletter (if = 17.694)

Collaborator: Zhejiang University School of Medicine

The service content provided by Zhongke New Life: Metabonomics

# 03

File name: Gut

Microorganism regulates acute myeloid leukemia by changing intestine.

Butyrate mediated barrier function

Published periodical: Nature Newsletter (if = 17.694)

Partner: Qilu Hospital of Shandong University

The service content provided by Zhongke New Life: non-target metabolism

# 04

Document Name: Response

Mechanism of Cold-tolerant Bacillus cereus D2 on Nickel (Ⅱ) Toxicity

The role of amino acids in reducing the toxicity of nickel (Ⅱ)

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Collaborator: College of Resources and Environment, Jilin Agricultural University

The service content provided by Zhongke New Life: Metabonomics

# 05

File name: Multiomics

The analysis revealed the shoot pair of torreya grandis.

Nano-plastic pollutants

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Collaborator: College of Forestry and Biotechnology, Zhejiang A&F University

Services provided by Zhongke New Life: Plant Metabolism Group

Article interpretation link: project article J.

Hazard Mater(IF 10.588)| Multivariate analysis reveals the molecular response mechanism of torreya grandis seedlings to nano-plastic pollutants?

# 06

File Name: Cadmium

The metabonomic characteristics of interference in pancreatic β cells are related to the following factors.

Spectrum of disturbed metabolites in human urine

Published periodical: Environment

International "(IF= 13.352)

Partner: The First Affiliated Hospital of Zhejiang University School of Medicine.

The service content provided by Zhongke New Life: Metabonomics

# 07

File name: riboflavin

Integrating cell energetics and cell cycle to regulate maize seeds

develop

Publication of the periodical Plant Biotechnology

Log (IF= 13.263)

Cooperative unit: Agricultural College of Henan Agricultural University

The service content provided by Zhongke New Life: targeted metabolism

# 08

File name: Lipids

TFEB-ERRα axis induced reprogramming enhanced membrane fluidity.

Promote the development of EC

Published periodical: Experimental Journal

& Clinical Cancer Research (IF= 12.658)

Partner: Fujian Maternal and Child Health Hospital, Affiliated Hospital of Fujian Medical University

The service content provided by Zhongke New Life: lipid group+metabolism group.

# 09

Document Name: Multistage

Metabonomics and genetic analysis confirmed the biomarkers of metabolites.

Syndrome and its genetic determinants

Published periodical: ebiomedicine (if =11.205)

Partner: Department of Epidemiology and Statistics, School of Public Health, Zhejiang University.

The service content provided by Zhongke New Life: Metabonomics

# 10

File name: Metabonomics

It is revealed that CAF-derived lipids promote peritoneal metastasis of colorectal cancer

By enhancing the fluidity of the membrane

Published periodicals: international periodicals

Biological science (IF= 10.75)

Partner: The Sixth Affiliated Hospital of Sun Yat-sen University.

The service content provided by Zhongke New Life: Lipomics.

# 1 1

File name: below

A large number of bacteroides and metabolic dysfunction are related to

Postweaning diarrhea in piglets

Publishing Periodical: Scientific Life in China

Science (IF= 10.372)

Collaborator: Institute of Animal Nutrition, Sichuan Agricultural University

Services provided by Zhongke New Life: non-target metabolism and data analysis.

Preface of Qualcomm survey.

# 0 1

Document Name: New

For triazole fungicides and

Coupled metabolic disorder

Publishing magazines: dangerous magazines

Materials (IF= 14.224)

Collaborator: School of Environment and Resources, Shanxi University

The service content provided by Zhongke New Life: RNA sequencing

# 02

File Name: Target

Based on the release of berberine/tannic acid self-assembly by traditional Chinese medicine

Treatment of ulcerative colitis

Published periodicals: advanced periodicals

Research (IF= 12.822)

Partner: State Key Laboratory of Quality Research of Traditional Chinese Medicine, Macau University of Science and Technology.

Services provided by Zhongke New Life: 16s sequencing.

Multi-group study joint article

# 0 1

File name: seasonality

Effects and Feedback of microplastics and Cadmium on Soil Biology

farmland

Published periodical: Environment

International "(IF= 13.352)

Partner: School of Environment, Nanjing University

Services provided by Zhongke New Life: 16s+ metabonomics.

Interpretation link of the article: Project article | 16S+ metabolism helps customers study soil pollution and land in the top journals of environmental science?

I hope that the above sharing can bring some scientific research ideas to researchers, and also hope that our products and services can provide more valuable help to everyone. In addition, teachers who are interested in our high-scoring customer articles can send us private messages, and we will sort out the package statistics and send them to you. Finally, I wish all teachers and students will continue to exert their efforts in the second half of 2022 and publish high-level SCI papers as they wish!