mass spectrometer/spectrograph/spectroscope
It is a method to identify and quantify the compounds in the sample by ionizing the sample and measuring its mass-to-charge ratio. In drug analysis, mass spectrometry can be used for quantitative and qualitative analysis of drugs and identification of metabolites.
2. Infrared spectroscopy technology
Infrared spectroscopy is a method to study the vibration and rotation of chemical bonds in sample molecules by measuring the absorption of infrared light by samples. In drug analysis, infrared spectroscopy can be used for qualitative analysis and structural identification of drugs. For example, the chemical composition, crystalline state and the existence of impurities of drugs can be identified by infrared spectroscopy.
3.？ Raman spectroscopy technique
Raman spectroscopy is a method to study the vibration and rotation of sample molecules by measuring the intensity and wavelength of Raman scattered light. In drug analysis, Raman spectroscopy can be used for qualitative analysis and structural identification of drugs. For example, Raman spectroscopy can be used to identify the chemical composition, crystallization state and the presence or absence of impurities of drugs.
4.？ High performance capillary electrophoresis
High performance capillary electrophoresis (HPCE) is a method to separate and analyze samples by high voltage electric field. In drug analysis, high performance capillary electrophoresis can be used for drug separation, identification and quantitative analysis. For example, different components in drugs can be separated by high performance capillary electrophoresis and analyzed qualitatively and quantitatively;
Common modern analysis methods
nuclear magnetic resonance technique
By measuring the * * * vibration frequency of the nucleus in the magnetic field, the structural information of the sample molecule can be inferred.
2.？ mass-spectrometric technique
By measuring the mass-to-charge ratio of ionized samples, the molecular weight and chemical structure information of sample molecules can be inferred.
3.？ Infrared spectroscopy technology
By measuring the infrared absorption of the sample, we can infer the functional groups and chemical bonds of the sample molecules.
4.？ Ultraviolet-visible spectroscopy technology
By measuring the ultraviolet absorption of the sample, the electronic structure and chemical bond information of the sample molecule can be inferred.
5.？ Chromatographic technique
By separating and analyzing the elution time of different components in the sample, the properties and content information of each component in the sample can be inferred.