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Pharmacological and Toxicological Effects of Huangqi Granules
Pharmacological research shows that it mainly has the following effects: 1, Astragalus membranaceus can invigorate qi and produce blood, and then has the effect of calming the nerves; It can obviously promote immune function and play the role of antioxidant enzymes. It can regulate the immune function of aged mice and is a good two-way immunomodulator. 2. Astragaloside can also achieve cardiotonic effect through Na and Ka-ATPase; The middle dose (4 mg) and high dose (8 mg) of Astragalus membranaceus have anti-heart failure effects. It can slow down the beating of beating cardiac myocytes and enhance the contractility of myocardium. 3. It can improve platelet adhesion, slow down heart rate and improve microcirculation to some extent. Astragalus can obviously reduce thrombosis and platelet adhesion. 4. Human experiments have proved that Astragalus has moderate diuretic effect, which can increase urine volume and chloride excretion.