Mo Xiumei, born in February, 196 1. Professor and doctoral supervisor of biomaterials and tissue engineering. Before returning to China, Professor Mo Xiumei was a postdoctoral fellow at Kyoto University in Japan, a researcher at National University of Singapore, a visiting researcher at Japan Institute of Industrial Technology, and a visiting professor at Aachen University of Industrial Technology Application in Germany. At present, he is the head of the research group of "biomaterials and tissue engineering" in the biomedical engineering discipline of Donghua University. He is a member of Singapore Materials Association, a member of Biomaterials Branch of China Biomedical Engineering Society, and a member of the editorial board of FrontiersofMaterialsScience magazine.

Chinese name: Mo Xiumei

Nationality: China.

Date of birth: 196 1 65438+ February.

Occupation: teacher

Main achievements: the first Pujiang talent

Masterpiece: National Natural Science Foundation: Study on the Structure, Properties and Application of Chitin.

Title: Professor of Donghua University

research direction

Biomaterials, nanofibers, tissue engineering, regenerative medicine.

1. Application of electrospun nanofibers in biomedicine, including regeneration of small blood vessels, nerves, skin, bones and cartilage, and slow release of drugs and active substances.

2. Research and development of new biomaterials, including the synthesis and application of medical hydrogels and degradable polymers.

3. Tissue engineering scaffold prepared by three-dimensional rapid prototyping and its application in bone and cartilage regeneration.

Main research results

1, a protein-polysaccharide two-component medical adhesive was prepared.

2. protein-polysaccharide composite nanofibers were prepared and successfully used to repair skin defects in rats.

3. Silk fibroin -P(LLA-CL) composite nanofiber catheter was prepared and successfully used for sciatic nerve repair in rats.

4. Collagen-chitosan -P(LLA-CL) composite nanofiber tubular scaffold was prepared and successfully used to repair the femoral artery defect in dogs.

5. Published more than 200 articles and conference papers, applied for more than 20 patents and granted 7 patents.

honour

1, the first Pujiang talent

2.2008 Summer Science Education Award

3. The first prize of Shanghai Technological Invention in 2008 "Preparation Technology and Application of Water-soluble Medical Chitosan"

4. The second prize of National Science and Technology Progress Award in 2009 "Development and Clinical Application of Water-soluble Chitosan Medical Products"

5, 2009-20 10 Donghua University "March 8th" Red Flag Bearer

project

1, National Natural Science Foundation: Study on the Structure, Properties and Application of Chitin

2. National Natural Science Foundation: Preparation and Properties of Polyethylene Glycol Grafted Chitosan

3. National Natural Science Foundation Project: Study on biomimetic interstitial space and cell interaction of collagen-chitosan composite nanofibers.

4. National Natural Science Foundation: Study on in vivo regeneration of small-caliber blood vessels.

5. National High-tech Research and Development 863 Program Nanomaterials and Devices: Study on protein-polysaccharide Composite Nanofibers for Tissue Repair.

6. Fund for Returned Overseas Students of Ministry of Education: Preparation and Characterization of Nanofibers and Their Application and Development in Tissue Engineering.

7. Sub-topic of major basic research project in Shanghai in 2005: Tissue engineering reconstruction of small blood vessels in basic scientific research of biomaterials related to tissue engineering.

8. Shanghai Yulan Science and Technology Talent Fund: Research on Small Diameter Vascular Tissue Regeneration.

9. Non-governmental international cooperation project of Shanghai Science and Technology Commission: Development of controlled-release activated nanofiber nerve conduits and heart valves.

10, Nano Project of Shanghai Science and Technology Commission: Study on Nanofiber Biomimetic Materials for Tissue Repair.

1 1. protein-polysaccharide -P(LLA-CL) composite nanofibers for small vessel tissue regeneration, a nano-project of Shanghai Science and Technology Commission.

Published papers

1, Chun, Jun, Cun Yifan, Xiu Mei Mo, Hong Jiang Ruan, Feng Fengli and the effect of core-shell nanofiber arrangement.

2. Su Yan, Qian Qian Su, Liu Wei, Malcus Rim, Jayaramarid Yevinu Gopal, Humemo, Siram Ramakrishna, Salem. Al-Deyab, MohamedEl-Newehy, controlled release of bone morphogenetic protein 2 and dexamethasone.

3. Lin Pengfan, Wang Hongsheng, Sunflower Zhang, Chuang Longhe, Zeng Xiaocai, Xiu Meimo, Regenerated Silk Fibrous Matrix Treated with 75% Ethanol Steam-Engineering Application biomaterial science Journal, Polymer Edition, 20 12, 23,497-508.

4. Yu Pijun, Wang Luping, Guo Lin, Alice Chan, Mo Xiumei, Collagen-chitosan composite nanofiber membrane for skin defect repair, China tissue engineering research and clinical rehabilitation, 201,15 (5 1): 9565438+.

5. Huang Chen, Yan Weitang, Liu Xin, Alexandra Suti, Qin Fick, Xiu Meimo, Xun Gai Wang, YosryMorsiandTongLin. Electrospun nanofibers with parallel surface structure for improving fiber growth, soft substance, 20 1 1, 7, 108 12-7.

6. Sunflower Zhang, An Linyin, Huang Chen, Wang Chunyang and Xiu Meimo. Degradation of LLA- chlorine blended nanofiber scaffold in vitro. Polymerization degradation and stability 20 1 196:2266-75

7. Ovida, Chen Rui, Spat, Josmoxi, Humemo. Arteryvesefabrication using the combined deposition modeling and electro spinning techniques. Rapid Prototyping Journal.2011; 17:37-44

8. Huang Longhe, Xu Xiaohong, Zhang Fan, Cao Lijun, Wei Feng, Wang Hongsheng, Xiu Meimo. Potential application of fibrinogen /P(LLA- Cl) hybrid nanofiber scaffold. journalofbiomedicalmaterialsresearch parta . 20 1 1； 97A:339-47

9. Sunflower Zhang, Q-ZYu, Xiumeimo. Preparation and intermolecular interaction of silk fibroin/hydroxybutyl chitosan blended nanofibers. international journalofmolecularsciences . 20 1 1； 12:2 187-99

10, sunflower Zhang, Yong Fang Qian, Wang Hongsheng, Lingpenfan, Huang Chen, Xiumeimo. Biomimetic extracellular matrix of electrospun fiber-hydroxybutyl chitosan nanofiber scaffold. JournalofBiomaterialsScience-polymer edition . 20 1 1； 22: 1069-82

1 1,, Chuanglonghe,, Feng, Wang, Mockers, etc. To manufacture gelatin-hyaluronic acid mixed scaffold with adjustable porous structure for soft tissue engineering. International journal biomacromolecules.2011; 48:474-8 1

12, Chen Feng, Ying-Zhu Jie, Kui Huazhang, Jin Wu, Ke-Wang Wei, Qi Litang, Xiu Meimo. Preparation and application of europium-doped calcium phosphate porous nanospheres, nano drug carrier, nano research letter 20 1 1, 6:67

13, Su Yan, Li Xiaoqiang, Liu Yinan, Sisu, Malcus Lin, Wei Qianqian and Humeimo, encapsulation and controlled release of electrospun (L- lactide -co-ε- caprolactone) nanofibers, biomaterial science Magazine-Polymer Edition.22 (2011).

14, Huang Chen, Chen Rui, Qin Feike, YosryMorsic, Sunflower Chapter, Xiumeimo. Electrospinning _ chitosan _ tpunanofibrosfolfsfortisseeen engineered tubular drafts, colloids and surfaces b: biointerfaces 82 (2011) 307 _ 315.

15, Yong, Kui Huazhang, Qin, Fei Kean and Xiu Meimo. Cross-linked gelatin and chitosan composite nanofiber tissue engineering scaffold, biomaterial science Journal 22 (2011)1099 _113.

16, Chun, Kui Huazhang, Cun Yifan, Xiu Meimo, Hongjiangruan, Feng Fengli. aligned natural _ synthetic polyblendnanofibersforperipheralnerveregeneration，acta biomaterial a 7(20 1 1)634 _ 643

17, Yu Pijun, Guo Lin, Mo Xiumei, protein-Experimental study on the application of polysaccharide composite nanofiber membrane in skin defect repair, china medical engineering, 20 10, 18(4), 1-4.

18, Feng Chen 1, Huang Peng, Xiu Meimo. Electrospun heparin capsule (LLA- Cl) core/shell nanofibers, Nano Biomedicine and Engineering 20 10/0,2,84-90.

19, Zong Gangchen, Pei Weiwang, B.Wei, Xiu Mei. Mo, Cui Fengzhen. Electrospinning-chitosan nanofibers: inorganic simulation materials-extracellular matrix-endothelial cells. actbiomaterialia . 20 10，6，372-382。

20. Sunflower Zhang, Yong Fang Qian, Wang Hongsheng, Lingpenfan, Huang Chen, Anlinyin and Xiumeimo. Genipin-crosslinked silk fibroin/hydroxybutyl chitosan nanofiber scaffold for tissue engineering applications. journalofbiomedicalmaterialsresearch parta . 20 10； 95A:870-8 1

2 1, Li Xiaoqiang, Su Yan, SPLiu, LJTan, humemo. Encapsulation of RamakrishnaS lactide-co-caprolactone fiber. Colloid and surface sb- biological interface.2010; 75:4 18-24

22. Chen Rui, Qin Fick and Xiu Meimo. Preparation and study of polyurethane/collagen composite nanofibers by electrospinning. aatccreview . 20 10； 10:59-63

23. Xiumeimo, Guangdu and Jihutian. atissueadhesiveevaluatedinvitroandivivoanalysis . journalofbiomedicalmaterialsresearch parta . 20 10； 94A:326-32

24. Preparation and application of chitosan/silk fibroin composite fiber by Zeng Xiaocai, Xiu Meimo, Kui Huazhang, Lin, An, Zhuang Long and Hong. Journal of Molecular Science 20 10, 1 1, 3529-3539

25. Sunflower Chapters, Wang Hongsheng, Huang Chen, Su Yan, Xiumeimo and Yoshida. Manufacture of LLA-CL nanofiber scaffold. Biomaterials Association

26. Sunflower Zhang, Xiumeimo, Huang Chen, Chuanglonghe and Wang Hongsheng. Silk fibers for electric stents and their cellular compatibility. Acta Biologica. 20 10/0,93 (3): 976-983.

27. Cai Jiugao, Chen Huazhang, Liu Wei, Zhou Xu and Xiu Meimo. Electrospun gelatin/hyaluronic acid scaffold and its cell compatibility. Nonlinear scientific letters d, 1, 67-72, 20 10.

28. Kui Huazhang, Hong, Cai Jiugao, Lin and Xiu Meimo. Eflectrospiningsilkfibroianditsb lendnanofibrousscafolfsfor Softtissue Engineering. Nonlinear Science

29. Chen Rui, Li Xiaoqiang, Qin Feike, Chuang Longhe and Xiu Meimo. Fabrication and Characterization of Collagen (Shell)/Thermoplastic Polyurethane (Core) Composite; Coaxial Electrospinning of Nanofibers. Electronic polymer, 20 10, No009: 1-8.

30. Chen Rui, Huang Chen, Qin Feike, Chuang Longhe, Wang Hongsheng, Xiu Meimo. Preparation and characterization of coaxial electrospun thermoplastic polyurethane/collagen composite nanofibers. Colloid and surface b: biological interface

3 1, Chen Rui, Qiu Lijun, Qin Feike, Xiu Meimo. Electrospinning thermoplastic polyurethane collagen-containing nanofibers for tissue engineering applications. Biomaterial science Journal: Polymer Edition, 20, 2009 (11):1513-36.

32. Chen, Yang, Moxi, Ou Weida, Xu Wenqing. Electrospinning of thermoplastic polyurethane tube and its application in the manufacture of artificial blood vessels. International Journal of Organ, July 2009, 32(7):459.

33. Chen Rui, Qin Feike and Xiu Meimo. Preparation and study of polyurethane-collagen composite nanofibers. AATCCReview, March/April, 20 10, 59-66

34. Chen Rui, YosryMORSI, ShitalPATEL, QinfeiKE, Xiumei Monovel Approach via Combination of Eletrospining and DMF for tri-leaf ether valves. China Frontier Materials Science.2009,3 (4): 359-366

35. Su Yan, Li Xiaoqiang, Wang Hongsheng, Chuanglonghe and Xiumeimo. Preparation and characterization of biodegradable nanofiber materials poly (L- lactic acid -co-ε- caprolactone). Journal of Materials Science: Materials Medicine

Su Yan, Li Xiaoqiang, Suiping Liu, Xiumei Moanda Ram. Biointerface, 2009,73 (2): 376-381

37. Su Yan, Li Xiaoqiang, Lingjiang Tancheng God, Xiumei Mo. Electrospun (L- lactide -co-ε- caprolactone) nanofibers are used to wrap and release protein continuously. Polymer 2009,17 (50): 4212-4219

38, Yong Fang, Li Xiaoqiang, Xiumei Mo. Preparation and characterization of polycaprolactone/copper chlorophyllin nanofiber materials. Journal of Iranian Polymer, 2009, 18(3):265-274.

39. Zong Gangchen, Weber, Xiu Meimo, Fu Yucui. Diameter control lecithin-collagen fiber. B:Polym。 Physics 2009,47:1949-1955

40. Zong Gangchen, Weber, Xiu Meimo, Lin Chaoqun, Ramakrishna, and Fu Zhai Cui. Mechanical properties of electrospun collagen-chitosan composite single fiber and membrane. Materials Science and Engineering 2009,29: 2428 _ 2435

4 1, Li Xiaoqiang, Su Yan, Xuzhou and Xiumeimo. Distribution of monooleate in poly (l- lactide-co-caprolactone) nanofibers. Colloids and Surface B: Biological Interface, 2009,69: 221-224.

42. Gray flowers and yellow flowers, Chuanglong River, Wang Hongsheng, and beautiful stranger. Preparation of core-shell biodegradable microfibers for long-term drug delivery. Biomaterials Association, 2009, 90a (4):1243 _1251

43. Li Xiaoqiang, Su Yan, Chuanglonghe, Wang Hongsheng, Xiumeimo. Astudyoftheelectrospinningofanh2o _ acetone _PCLTernarySystem Polymer and chemistry. Polymer composites, 2009, 17( 1):37-40.

44. Li Xiaoqiang, Su Yan, Chen Rui, Chuanglonghe, Wang Hongsheng, Xiumeimo. Preparation and properties of P(LLA-CL) nanofibers with core-shell structure. Japan Polymer Science, 2009,11:1564 _1570.

45. Li Xiaoqiang, Su Yan, Chuanglonghe, Wang Hongsheng, Fenghao and Xiumeimo. Endothelial cell interaction between sorbitan monooleate and poly (L- lactide -co-ε- caprolactone) electrospun nanofibers. Biomaterials Association, 2009 1 Feb,1,878-885

46, Chen Feng, Su Yan, Xiumei film, etc., biocompatibility, alignment, etc.