The difficulty of publishing SCI papers varies from person to person, but in general, it is a relatively difficult process for most college students. The following are some factors that may affect the difficulty of publishing SCI papers for college students:

1. academic background and knowledge reserve: publishing SCI papers requires a solid academic background and knowledge reserve. For non-science majors, this may require extra efforts to learn and master knowledge in related fields.

2. Research experience and skills: publishing SCI papers usually requires independent research work. For college students, this may be a challenge, because they may lack practical research experience and skills. However, college students can accumulate these experiences by participating in tutor's research projects or laboratory work.

3. Time and energy input: It takes a lot of time and energy to publish SCI papers. College students usually need to balance the needs of course study, extracurricular activities and personal life. Therefore, they may need to finish their research work and write papers in a limited time.

4. Resources and support: publishing SCI papers requires certain resources and support, including experimental equipment, data acquisition and processing capabilities. For college students, they may not get the same resources and support as professional researchers. However, college students can still carry out research work by cooperating with other researchers or using the resources provided by the school.

5. Language and cultural barriers: Publishing SCI papers usually requires writing and communication in English. This may be a challenge for non-native English-speaking college students. In addition, there may be cultural differences between different disciplines, which may also lead to difficulties in communication and understanding.