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Is titanium dioxide edible?
Question 1: Can titanium dioxide be used as a food additive? Is it harmful to human body? Titanium dioxide is a stable metal oxide. Titanium dioxide with high purity and low content of harmful metal elements can be used as food additives because of its strong inertia, high whiteness and hiding power. For example, the titanium dioxide white pigment produced in Shanghai is specially used as a food additive, which is generally used in xylitol, jelly, candy, flour, fish balls, drinks and so on! This is approved by the State Quality Supervision Bureau, and there is no problem in using titanium dioxide as a food additive.

What you said is harmful to human body, but I need to answer it for you. Some food factories or cosmetics factories use industrial titanium dioxide as food additives, and its harmful metals, such as arsenic, lead, mercury and antimony, are not up to standard, so this statement is definitely harmful!

Question 2: Is titanium dioxide (titanium dioxide) edible? Is it harmful to human body? Titanium dioxide (TiO2) has stable chemical properties and generally does not react with most substances. There are three kinds of crystals of titanium dioxide in nature: flaky titanium, anatase and rutile. Electroplated titanium is an unstable crystal form and has no industrial use value. Anatase and rutile are stable crystal lattices and are important white pigments and enamels. Compared with other white pigments, they have superior whiteness, coloring power, hiding power, weather resistance, heat resistance and chemical stability, especially non-toxic. Titanium dioxide is widely used in coatings, plastics, rubber, printing ink, papermaking, chemical fiber, ceramics, daily chemicals, medicine, food and other industries. The coating industry is the biggest user of titanium dioxide, especially rutile titanium dioxide, which is mostly consumed by the coating industry. The paint made of titanium dioxide has bright colors, high hiding power, strong coloring power, small dosage and many varieties, which can protect the stability of the medium, enhance the mechanical strength and adhesion of the paint film, prevent cracking, prevent the penetration of ultraviolet rays and moisture and prolong the life of the paint film.

Titanium dioxide (commonly known as titanium dioxide) generally does not react with most substances. However, the parts of the human body in contact with the outside world have corresponding defense mechanisms to prevent harmful substances from entering. However, these defense mechanisms have limited effect on nano-TiO2 particles. Respiratory tract, epidermis and digestive tract are the three main parts where nanoparticles invade human body. Generally speaking, respiratory tract contact with nanoparticles is the most common way, so the most research on the biotoxicity of nano-titanium dioxide is lung toxicity. 2. Toxic effect of1on lung: After the lung is exposed to insoluble particles, with the extension of exposure time, inflammatory symptoms such as proliferation of inflammatory cells, injury of alveolar epithelial cells and increase of lung weight appear one after another. Zhang et al [using 1mg of 30nm nanometer titanium dioxide? L- 1 was injected into mice. After 30 days, it was found that the lung weight of mice increased significantly, while the total number of lung cells decreased by 50%. Afaq et al. [] also confirmed that ultrafine titanium dioxide (20nm) particles can cause interstitial lung tissue, induce inflammatory reaction and increase epithelial tissue permeability. Warheit et al [Research shows that nano-TiO _ 2 can cause instantaneous inflammation and cell damage within 24 hours. 2.2 Toxic effects on heart, liver, kidney, brain and other tissues. Nano-titanium dioxide can be transported to various organs, including the brain and heart, and has toxic effects on other organs because of its small particle size. Studies have confirmed that nano-TiO _ 2 can cause pathological changes in the circulatory system. Nurkiewicz et al. [found] Dropping 0. 1 or 0.25mg titanium dioxide with a particle size of 1μm into rat trachea for 24h caused dose-dependent damage to vascular endothelial cells. When Wang et al. [] studied the acute toxicity of titanium dioxide at 25 nm, 80 nm and 155nm, they found that 5g? After oral administration of kg- 1, two weeks later, it was found that the heart damage caused by 25 and 80nm groups was more serious than that caused by 155nm group. Titanium dioxide at 80 nm and 155nm also caused vacuoles in hippocampal neurons, indicating that there was fatty degeneration in the brain and that nano-titanium dioxide was neurotoxic. At the same time, the liver coefficient of mice in 25 nm and 80nm groups increased obviously, indicating that nano-TiO _ 2 can trigger inflammatory reaction in mice's liver. Pathological examination also found edema and necrosis of hepatic lobules. 80nm TiO _ 2 mainly accumulates in the liver, which proves that nano-TiO _ 2 has hepatotoxicity. At the same time, it was also found that there was a large amount of protein in the renal tubular fluid of mice in the 80nm group, and severe glomerular swelling occurred in the 155nm group, indicating that nano titanium dioxide was toxic to the kidney. Baan et al.' s research shows that pigment-grade titanium dioxide is potentially carcinogenic to human beings.

Question 3: medical use of edible titanium dioxide: in pharmaceutical preparation, it can be used as a white colorant to prepare film-coated suspension, sugar-coated capsules and gelatin capsules, can also be mixed with other colorants for skin preparations, and can also replace starch as a pharmaceutical excipient. Food: used for candy coating, preserved fruit, jelly, chewing gum, solid beverage without sweetener and concentrated solid beverage, milk beverage and puffed food. Candied fruit (spoken language), jam, salad dressing, mayonnaise and other foods that need whitening. Cosmetics: foundation, powder cake, sunscreen, eye shadow, lipstick, lipstick, toothpaste, talcum powder, prickly heat powder, cream and white soap.

Question 4: Is titanium dioxide edible? Titanium dioxide cannot be eaten directly.

Question 5: Is titanium dioxide harmful to health? Titanium dioxide /...8

A few days ago, a European research institute committed to protecting human health in the fields of environment, workplace and food issued a proposal: it is required to define titanium dioxide (titanium dioxide) as a carcinogen!

The French Agency for Food Environment and Occupational Health and Safety (ANSES) pointed out in the document that titanium dioxide is commonly used in coatings, building materials and other industrial and daily consumer goods. According to the research results, it is suggested that it should be classified as a 1B carcinogen that may cause cancer through inhalation.

The European Chemicals Agency (ECHA) has released the document submitted by ANSES on May 3, 20 16, which requires titanium dioxide to be included in the unified classification of hazardous substances.

At present, this document is being consulted in EU countries, and the deadline is 2065438+July 65438+May 2006. After that, ECHA will have 65,438+08 months to consider and submit the final proposal to the European Commission.

As a white inorganic pigment, titanium dioxide comes from rocks and minerals and has been used in many products for decades.

According to the Titanium Dioxide Sub-center of the Productivity Promotion Center of the National Chemical Industry, according to ECHA CLP regulations (classification, labeling and packaging of substances/mixtures), if ANSES' proposal to classify titanium dioxide as 1B (human carcinogen) is accepted, all coatings containing titanium dioxide within the EU will probably be classified as carcinogens, and the affected countries will involve 28 EU member States as well as Iceland, Liechtenstein and Norway.

However, in the field of consumption, the use of carcinogens listed as 1A and 1B in CLP regulations is restricted, which means that coatings containing titanium dioxide in the formula will probably withdraw from the consumer retail field and can only be sold to professional users.

And once the European Council formally approves this document, environmental organizations around the world are likely to refer to the classification of the European Union, so that the global paint market will be affected!

For this document of ANSES, TDMA, a non-profit organization under the European Chemical Industry Council, issued a response statement, saying that it had carried out a classified evaluation study on titanium dioxide six years ago. According to this assessment report, within the scope of EU chemical REACH regulations, "based on scientific and effective research and assessment, titanium dioxide should not be classified as a toxic substance in any form". In addition, the results of an epidemiological study are the same as this conclusion. This study investigated the working conditions of 20,000 workers in 15 titanium dioxide manufacturing plants for decades, and the results showed that frequent contact with titanium dioxide would not harm their health.

TDMA said that it will announce the new findings and research progress of this product evaluation in time. At the same time, the association also said that it would "carefully study" the French proposal and provide detailed answers to ECHA's public consultation.

According to the data of China Titanium Dioxide Industry Technology Innovation Strategic Alliance, a paper by the International Agency for Research on Cancer (IARC) studied the carcinogenicity of titanium dioxide.

The paper points out that in the process of titanium dioxide production in the United States and Europe, the occupational exposure levels of workers exposed to titanium dioxide were screened in 1970 and 2000 respectively. Although the exposure level of related occupations such as site cleaning and maintenance is very high, the highest exposure level is titanium dioxide packaging and grinding, and the average occupational exposure level of inhalable dust reaches 6 mg. At present, there is no ready-made data to specify or quantify the occupational exposure standard of "ultrafine titanium dioxide" dust. However, workers in titanium dioxide production plants are not only exposed to titanium dioxide dust, but also directly exposed to particles such as ore powder, dust, strong acid and asbestos fiber.

In North America and Western Europe, three groups of "epidemiological cohort studies" and one group of "population-based case-control studies" were conducted to evaluate whether titanium dioxide can cause human cancer. The largest group of "epidemiological cohort studies" is aimed at workers in titanium dioxide industry, who come from six European countries. & gt

Question 6: Is titanium dioxide edible? As a food additive, food-grade titanium dioxide can be eaten, but not much. The body's ability to digest titanium dioxide (titanium dioxide) is not very strong. The correction fluid can't be eaten, because it contains organic solvents such as methylcyclohexane, which is toxic.

Question 7: Reference dosage and application scope of edible titanium dioxide. Remarks on maximum dosage: 1, preserved fruit 10g/kg2, cocoa products, chocolate and chocolate products (including chocolate products and chocolate substitutes), candy 2.0g/kg3, hard candy 10g/kg4, polishing sugar 5 and gum 5.0g/ Kg6. The coating of candy chocolate products should be used properly according to the production needs. 7. Decorative candy (such as craft modeling or cake decoration), top decoration (non-fruit material) and sweet juice 5.0g/kg8, mayonnaise and salad dressing 5.0g/kg9, solid beverage 10 and jelly 5.0g/kg shall be properly used according to production needs. If it is used in jelly powder, the dosage will be increased by 1 1, fried snacks 10g/kg 12, puffed food 10g/kg 13 and others (beverage turbidity agent)/kloc.

Question 8: Is titanium dioxide poisonous? Someone who specializes in producing titanium dioxide will answer your question.

Titanium dioxide, commonly known as titanium dioxide, must tell you that it is nontoxic.

It's okay to eat a little.

The dose problem mentioned upstairs is also the physical damage caused by titanium dioxide dust, not the damage caused by toxicity.

The above is pure titanium dioxide, which is the finished titanium dioxide.

If it is an intermediate, such as hydrated titanium dioxide, it is harmful. This is called metatitanic acid, and the intermediate in production contains a lot of sulfuric acid.