Long-term or repeated effects caused by one or more reasons.

Causing the liver to harden.

The resulting diffuse liver injury.

What causes liver cirrhosis?

Let's listen to Dr. Tongji.

Tongji hospital: Yang Changqing.

0 1 When will liver disease become cirrhosis?

Among all kinds of liver diseases, chronic viral hepatitis is the most likely to cause cirrhosis, such as hepatitis B and hepatitis C. Hepatitis B is the most common in China, so it should be the most common viral hepatitis.

hepatitis virus

Hepatitis virus infection is one of the main causes of liver cirrhosis. Many people think that viral hepatitis infection is not serious, there are no serious symptoms, and it doesn't matter if life is not affected. In fact, this view is wrong Many clinical cases show that patients with hepatitis B and C can develop liver fibrosis or even cirrhosis if they are not actively diagnosed and treated. Hepatitis C patients can be completely cured now if they are treated actively in the early stage. Because chronic hepatitis virus accumulates in patients for a long time, the virus keeps replicating, causing very serious damage to the liver, which in turn leads to the formation of liver fibrosis and cirrhosis. This is why hepatitis virus becomes liver cirrhosis. It should be reminded that the course from viral hepatitis to liver fibrosis and even cirrhosis is as short as several months and as long as several decades.

Acute alcoholism

Patients with common liver diseases around them will be asked to give up drinking. In fact, this is because alcohol and its intermediate metabolite acetaldehyde can cause direct damage to the liver. For people who often drink alcohol, the probability of cirrhosis is much higher than that of ordinary people, because their liver has been damaged by alcohol for a long time. Therefore, drinking alcohol is one of the forming factors of liver cirrhosis. Drinking more than 40 grams a day (equivalent to liquor 100 ml, red wine 500 ml and beer 1000 ml) may lead to alcoholic hepatitis after five years.

In addition, even if you don't drink alcohol, some patients with fatty liver can gradually evolve into liver fibrosis or even cirrhosis.

How to prevent liver cirrhosis?

Liver cirrhosis caused by hepatitis occurs under the specific circumstances of severe liver injury and recurrent or persistent hepatitis. Recurrent hepatitis evolves into cirrhosis, and there is still a link in the middle, that is, liver fibrosis.

Liver fibrosis in China is mainly caused by viral hepatitis, which promotes the continuous expansion of liver fibrosis. Therefore, there are two main links to prevent the occurrence of liver cirrhosis: antivirus and prevention of liver fibrosis. Removing the cause is the most useful measure to prevent liver fibrosis and cirrhosis. For chronic viral hepatitis with repeated activities, antiviral treatment is fundamental, followed by active liver protection, anti-inflammation and prevention of liver fibrosis.

Alcoholic patients should give up drinking, and those with alcoholic liver injury continue to drink, almost all of them can develop cirrhosis.

Patients with fatty liver usually pay attention to the regulation of diet, mainly low sugar, high protein and light food.

Adequate rest is very necessary, and excessive fatigue and mood swings will promote the further development of the disease.

In a word, the main factors of liver cirrhosis in hepatitis patients are virus activity and repeated inflammation, so I hope hepatitis patients will pay attention to it. As long as it is handled properly, cirrhosis can be prevented to some extent.

Expert business card

Yang Changqing

Tongji hospital affiliated to Tongji University

Chief physician, professor and doctoral supervisor of gastroenterology.

Special needs clinic: Monday afternoon

Expert clinic: Thursday morning

Endoscopic diagnosis and treatment: Tuesday morning (gastroscopy, colonoscopy) and Wednesday morning (colonoscopy, colonoscopy, etc. )

Clinically, he is good at the diagnosis and treatment of complicated and difficult hepatobiliary diseases and gastrointestinal diseases, especially the diagnosis and treatment of portal hypertension and its complications (such as esophageal varices and intractable ascites) and the endoscopic diagnosis and treatment of digestive system diseases.

He studied in Harvard Medical School in the United States, and is now an outstanding academic leader in Shanghai, an expert in quality control of digestive diseases in Shanghai, a member of American Gastroenterology Association (AGA), American Association for the Study of Liver Diseases (AASLD), vice president of Digestive Branch of China Geriatrics Association, member of the Standing Committee of Digestive Branch of Chinese Medical Association, member of Endoscopic Group, member of Digestive Branch of Chinese Medical Association, and deputy head of portal hypertension group of China Research Hospital Association. Member of hepatobiliary cooperation group and difficult and severe cooperation group of Digestive Branch of Chinese Medical Association, member and secretary of Pharmacology Group of Hepatology Branch of Chinese Medical Association, vice chairman and head of hepatology group of Shanghai Society of Integrated Traditional Chinese and Western Medicine, vice chairman and head of pharmacological hepatology group of Shanghai Medical Association, standing Committee member and secretary of Digestive Branch of Shanghai Medical Association.

Up to 20 18, more than 230 papers have been published, including more than one SCI paper 100. He has presided over a number of national and provincial scientific research projects, including key projects and general projects of the National Natural Science Foundation, and won four provincial scientific and technological progress awards 1 item and third prize.

Text | Gastroenterology

Figures | The above are all copyright figures.

Editorial Department | Propaganda Department