1984 graduated from Shandong medical college, 1984- 1986 worked in the Department of Neurology, Beijing China-Japan Friendship Hospital, and 1989 obtained a master's degree in medicine from peking university health science center. The tutor is Professor Chen Qingtang, and the topic of the thesis is "Changes of neuromuscular joints with age in normal people". 1992- 1997 studied in Germany, and studied neuropathology at the Institute of Neuropathology, Medical College of Essen University, Bremen Eastern Central Hospital and Mainz University. 65438-0996, Doctor of Medicine, University of Essen, Germany. The tutor is Professor Gerhard. The topic of the thesis is "Pathology and pathogenesis of central nervous system amyloidosis". After that, he continued to study the pathology of neuromuscular diseases with Professor Gaubert as a visiting doctor at Mainz University. After returning to China from 65438 to 0997, he worked in the Department of Neurology, the First Hospital of Peking University for clinical, scientific research and teaching. In clinical and scientific research, nervous system diseases are mainly diagnosed through pathological research, with emphasis on pathological and genetic research of peripheral neuropathy and myopathy. The research team published more than 70 papers/kloc-0 at home and abroad, mainly involving peripheral neuropathy, myopathy and central nervous system diseases. Participate in the compilation of neurology monograph 1 1. Supported by the Ministry of Education, National Natural Fund, Beijing Natural Fund and Research Fund of Peking University Disease Gene Center.