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Antibacterial spectrum and clinical application of natural penicillin
For gram-positive bacteria and a few gram-negative bacteria, it is ineffective for most gram-negative bacteria (aztreonam or aminoglycosides are needed)

Preferred natural penicillin:

Streptococcus hemolyticus infection

Streptococcus pneumoniae infection

Staphylococcus infection without penicillinase production (MRSA chooses rifampicin+vancomycin or linezolid)

anthrax

tetanus

gas gangrene

Syphilis (currently using benzathine penicillin)

spirochete

Aminoglycosides in the Treatment of Endocarditis Caused by Streptococcus viridis

recurrent fever

Penicillium can be used for:

epidemic cerebrospinal meningitis

Radiobacterosis

Gonorrhea (spectinomycin)

rat-bite fever

Vulnerable bacteria other than anaerobic bacteria infection.