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Calculation of sample size in medical open questions
The calculation methods of sample size of medical problems include hypothesis testing, correlation and reliability.

First, the method based on hypothesis testing.

This method is suitable for comparing the differences between two or more groups, such as comparing the effect differences between the treatment group and the control group. In this method, it is necessary to determine the significance level (usually 0.05) and statistical power (usually 0.8) in the study, as well as the expected effect size. According to these parameters, the minimum sample size can be calculated by statistical method.

Second, the method based on correlation.

This method is suitable for studying the correlation between variables, such as index values used for disease prediction. In this method, it is necessary to determine the required significance level and statistical power, as well as the expected correlation coefficient. According to these parameters, the minimum sample size can be calculated.

Thirdly, the method based on credibility.

This method is suitable for studying the reliability of measuring tools, such as questionnaire survey. In this method, it is necessary to determine the required level of significance and statistical power, as well as the expected level of credibility. According to these parameters, the minimum sample size can be calculated.

The writing method of medical open report.

The opening report of medical topic selection is an explanatory report written by graduate students on the topic selection and research implementation after completing the literature research. Writing a qualified opening report is the premise of graduation thesis writing, which can provide ideas and guidance for subsequent thesis writing.

First, the basic content of the opening report

1, the purpose and significance of the paper

Clarify the purpose and significance of the research, explain why this topic is chosen and the importance of the research.

2. Summary of domestic and foreign research

Summarize the research status of related fields at home and abroad, including the existing research results, viewpoints and methods.

3. The main problems to be solved in this paper.

Clarify the specific academic problems to be solved in the paper, that is, the innovation of the paper.

4. The main content (outline) of the paper to be written.

List the main chapters and contents of the paper, and give the preliminary research framework and ideas.

5, paper schedule

Plan the time arrangement and progress of the paper, including literature research, experimental design, data analysis, etc.

6. Others

Other relevant contents can be supplemented according to specific conditions, such as research methods, data sources, expected research results, etc.

Second, the writing steps of the opening report

1, research background (literature review)

This paper expounds the background and significance of the research topic, answers why we should study this topic, and summarizes the present situation and trend of related research at home and abroad.

2. Purpose and significance

Explain the purpose and significance of the research, and explain the practical significance and theoretical value of the research topic.

3, the implementation plan

Describe the research content, process and method design in detail, including research direction, sub-topics and research methods.

4, complete the safeguard measures

Explain the guarantee measures to complete the research task, such as data collection, experimental equipment, research team, etc.

5. Expected research results

Explain the expected research results and contributions to the academic field.