According to the British "Guardian" report, Cambridge University cooperated with barbera Han Institute to develop the technology of "instant reprogramming when mature", which successfully restored 53-year-old female skin cells to 23 years old. This paper was published in eLife magazine.
Just as trees grow with rings, when people grow up, there are signs of aging in their cells. British scientists used a chemical mixture to re-edit cells in a 13-day experiment to eliminate the aging traces of old cells. Treated skin cells produce more collagen and move faster, thus accelerating wound healing and showing more signs of excitement and vitality.
The researchers said that this kind of surgery is also suitable for other tissues of the human body, and it shows "encouraging effect" in treating aging-related diseases. Dr. Diljit Gil, the core figure, said that the technology was based on the breakthrough of shinya yamanaka, the Nobel Prize winner in 20 12 years, and its inspiration came from how the old cells of parents were transformed into young tissues of newborns.
Compared with previous studies, "instant reprogramming when mature" technology will not reverse mature cells into newborn cells without any skills, but restore them to a young state on the premise of maintaining their functions, just like most people prefer to keep their bodies when they are 18 years old, rather than newborn babies who can't walk yet.
This magical operation of "rejuvenation" is still in the laboratory stage. Billionaires from Silicon Valley can't wait to use other methods, such as "exchanging blood". In 2005, Stanford University proved that the age of the old mouse decreased by 19%-28% in three months by * * * "averaging" the age of two mice.
According to Gawker, peter teale, the author of From 0 to 1 and the co-founder of Paypal, spends $40,000 every quarter on the fresh blood of young people aged 18 in an attempt to live to 120. There are more than 600 rich people like Peter, and there is even a blood exchange industry that provides such services at a price of $8,000 per liter: it is obtained from young people aged 18-25 and injected into the elderly and infirm rich.
"Instant reprogramming at maturity" and "blood exchange" both sound a little magical. Scientists at Harvard University have invented a more conservative NAD-Aimuyin assistant technology. NAD, as the most abundant molecule except water in human body, participates in the tricarboxylic acid cycle in vivo, and promotes the normal operation of the body by synthesizing longevity protein and enhancing immunity. Studies have shown that with the aging of the human body, the content of this molecule gradually decreases, and it can achieve a certain degree of aging reversal after supplementation.
In mouse experiments, the survival time of precursors was prolonged by nearly 1/3. In clinical trials, the elderly over 65 years old showed positive effects on improving muscle strength and insulin resistance after eating for 3 months. The finished product "Aimu Printing" has been approved in Jidong, China. Due to strong demand, it expanded its 200-300 ton factory in Yuyao, Zhejiang, and passed the certification of FDA-GRAS and the National Medical Products Administration for raw materials filing.
The storm from the scientific community even blew into research institutions in various countries. The British government claims that it will conquer aging in 10. In the view of life science, it regards "loving mother's drink" as one of the means to achieve this goal. SOCOM, the special operations command of the United States, has begun to be militarized, thinking that it can delay the decline of the body and enhance the capabilities of the army. I have to say that every official move sometimes becomes a weather vane.
In addition, Israeli scientists claim that after inhaling high-pressure pure oxygen for three months, aging cells can be destroyed by 37% and telomeres can be prolonged by 20%, which is equivalent to being 25 years younger. Basketball star James and pop singer Justin Bieber are using it. At present, the domestic hyperbaric oxygen chamber O2 ARK only appears in Shanghai and Beijing because of its high price, ranging from hundreds of thousands to millions.
Whether it is crazy instantaneous cell programming, blood exchange, or the supplementary technology of NAD and hyperbaric oxygen chamber that has gradually become the mainstream, it reflects the rapid development of medical level in 2 1 century. According to the statistics of analysts of Bank of America Merrill Lynch, a famous investment bank, after 2020, medical knowledge will double every 73 days, which may be an important reason for the large number of life-sustaining technologies.
A Brief History of the Future describes the prospect of mankind: "Plague, war and hunger, which once threatened the survival for a long time, have been conquered, and there are only three topics before Homo sapiens: eternal life, happiness and becoming an upgraded human with' divinity'." Judging from the current trend, historians' predictions are gradually becoming a reality.