Chen Yazhu, female, born on July 23rd, 1936, native of Ningbo, party member, Zhejiang Province, expert in high voltage technology, expert in biomedical engineering, academician of China Academy of Engineering, professor and doctoral supervisor of Shanghai Jiaotong University, honorary dean of the School of Biomedical Engineering of Shanghai Jiaotong University.

From 65438 to 0962, Chen Yazhu graduated from the Department of Electrical Engineering of Shanghai Jiaotong University, majoring in high voltage technology. After graduation, she engaged in higher education and scientific research in Shanghai Jiaotong University. 1996 was elected as an academician of China Academy of Engineering.

Chen Yazhu mainly studies high-voltage new technology and insulation detection, physical factor tumor treatment technology (radio frequency, ultrasonic wave, electromagnetic wave and other physical factors), comprehensive tumor treatment mechanism research (hyperthermia combined with radiotherapy/chemical/gene therapy), optical detection technology, biomedical intelligent instruments and so on.

Chinese name: Chen Yazhu

Nationality: China.

Ethnic group: Han nationality

Date of birth:1July 23, 936

Occupation: educational and scientific research worker

Graduate school: Shanghai Jiaotong University

Main achievements: 1996 was elected as an academician of China Academy of Engineering.

Masterpiece: medical physics

Gender: Female

Native place: Ningbo, Zhejiang

Degree: Bachelor's degree

Party member, China.

Character experience

1936 On July 23rd, Chen Yazhu was born in Ningbo, Zhejiang.

1September 1957 to1July 1962, studied at Shanghai jiaotong university and obtained a bachelor's degree in high voltage.

/kloc-0 joined the China * * * production party in July, 960.

From September 65438 to September 0962, he began to engage in higher education and scientific research in the Department of Electrical Engineering of Shanghai Jiaotong University.

1August, 988, he began to serve as the director of the Institute of Biomedical Instruments of Shanghai Jiaotong University.

1996, elected as an academician of China Academy of Engineering.

In 2008, Chen Yazhu founded Shanghai Med-X Physical Therapy and Testing Equipment Engineering Technology Research Center and served as the director of the center.

20 1 1, Chen Yazhu cooperated with Easy Magnetic Materials Co., Ltd. to establish an academician workstation.

2065438+In May 2006, Shende (Ningbo) Medical Device Technology Co., Ltd., invested and built by R&D team with Academician Chen Yazhu as the chief consultant, signed a contract.

Major achievements

achievements in scientific research

Chen Yazhu has worked in the fields of overvoltage lightning protection, insulation design of high-voltage equipment and numerical calculation of electrostatic field. In the early 1980s, she applied multidisciplinary knowledge and engineering technology to the field of non-invasive medical treatment, and successfully developed an "electro-hydraulic shock wave extracorporeal kidney calculi pulverizer" without scalpel method in the history of urology, which enabled patients with kidney calculi and urinary calculi to receive painless and non-invasive treatment, with a clinical effect of over 98%. The popularization and application have achieved social and economic benefits. As a self-developed medical equipment, it has been applied in major hospitals, and more than 90% patients in kidney calculi have received non-invasive treatment.

In 2000, Chen Yazhu was the first in the world to put forward the technical idea of "multi-mode phased focused ultrasound non-invasive treatment of tumors", combining chemical drugs or heat-sensitive liposome drugs to convert systemic chemotherapy into local chemotherapy and reduce the side effects of chemotherapy. This treatment method has the advantages of non-invasion, non-trauma, no side effects and quick recovery, which has attracted the attention of biomedical engineering circles.

Since 265438+20th century, Chen Yazhu has devoted himself to the clinical research and application development of tumor physical therapy, and put forward a "green" multi-mode treatment concept, that is, a diversified treatment mode combining local ultrasonic hyperthermia with chemotherapy and radiotherapy. China took the lead in putting forward the new concept and technology of phased array ultrasonic multi-mode focusing, and achieved innovative and new research results. The concept and method of ultrasonic therapy have been popularized and developed, and have been widely recognized internationally. And build a number of digital equipment Industry-University-Research win-win and mutually beneficial platforms, and many research results have been transformed or are being transformed.

Tang Yaozong, Chen Yazhu, Chen Wenzhen. Study on multipole gap. High pressure technology, 1979(02): 13-25.

Chen Yazhu, Tang Yaozong. Measurement and analysis of large impulse current of lightning protection distribution transformer and lightning arrester combination. Journal of Shanghai Jiaotong University,1979 (04):157-167.

Chen Yazhu, Tang Yaozong. Lightning protection of distribution transformer. Electric power technology, 1980(0 1):27-33.

Tang Yaozong, Chen Yazhu. Analysis on the effect of GSW lightning arrester without freewheeling to protect distribution transformer. High voltage electrical appliances,1981(04): 7-12.

Chen yazhu. Study on two-dimensional electric field with open boundary by finite element method. Electric Power Technology, 1984(06):33-38.

Chen yazhu. Computer aided analysis of potential distribution of EHV arrester. High pressure technology,1985 (02):14-18.

Zhang Ren 'an, Miao Zhongliang, Dong Huiqun, Qiu, Tang Yaozong, Chen Yazhu. Kidney calculi was crushed by extracorporeal shock wave. Journal of Clinical Urology, 1986(02):65-67.

, Luo, Yu Xionglong, Chen Yazhu. Research and application of urine flow rate measurement method. China Journal of Medical Devices,1997 (02): 91-92+90.

Zeng Qingji, Hu Weisi, Chen, et al. Reconfigurable wavelength routing all-optical network test bench//Photonics China '98. 1998.

Huo Yanming, Li Guowei, Chen Yazhu. Design of ultrasonic array transducer and sound field simulation. Acoustics,1999 (04):168-172.

Huo Yanming, Chen Yazhu. Estimation of temperature distribution of sound field focus of spherical self-focusing transducer. Beijing Biomedical Engineering, 2000(04):2 12-2 16.

Dan, Lily, Chenitz. Transport parametersofelectronic swarsins SF 6 andargongasmixes. Japanese Journal of Applied Physics, 2000,39 (Part 2, No.3A/B): L244-L245.

Huo Yanming, Chen Yazhu. Analysis of sound field characteristics of several rotating arc self-focusing transducers. Journal of Acoustics, 2001(01):13-18.

An Ling, Jiang Xiuchen, Zhu Yu, Han Zhendong, Chen Yazhu. Object-oriented design and implementation of condition-based maintenance software system for transmission lines. Power System Automation, 2002(07):66-69.

Sun Junxi, Chen Yazhu, Gu. Multi-scale edge detection based on edge representation of hidden Markov model. Chinese journal of computers, China, 2003(04):497-50 1.

, Xiao, Sun Junxi, Bai Jingfeng and Chen Yazhu. Application of multimodal image registration technology in HIFU surgery. Journal of Biomedical Engineering, 2004 (June): 935-938.

, Chen Yazhu, Chen. Design and implementation of elevator embedded monitoring terminal. Automation Instrument, 2005(0 1):46-48.

Song, Song, Chen. Early diagnosis system based on computer. Meeting process:. IEEE international annual conference on engineering medicine and biomedicine. Conference of Medical and Biological Society of Electrical and Electronic Engineering, 2005, 6:6608-6665438.

Gu,,, Chen Yazhu. Anatomical and morphological study on subchondral bone of acetabulum. China Journal of Clinical Anatomy, 2006(0 1):50-53.

, Zhang Su, Zhang _, Chen Yazhu. Modeling and simulation of phased array focused ultrasound ablation of tumor. Journal of System Simulation, 2007 (01):164-167.

Xu, Bai Jingfeng, Chen Yazhu. Effect of water cooling temperature on thermal damage during water cooling radiofrequency ablation. Beijing Biomedical Engineering, 2008(04):393-395+4 12.

Gu, Chen Yazhu. Prediction of mechanical properties of osteoporotic bone. Medical Biomechanics, 2009,24 (01): 70-73.

Diao, Shen E,,, Chen Yazhu, Sun Jianqi, Hu Bing. Ablation effect of alternating hot and cold tumor therapeutic instrument on visual tissue model. China Medical Imaging Technology, 20 10/0,26 (11): 2034-2036.

Meng _, Bai Jingfeng, Chen Yazhu. Modeling and calculation of acoustic field distribution of phased focused ultrasound in bilayer tissue. China Journal of Medical Physics, 20 1 1, 28 (02): 2567-2570.

Suo Shiteng, Zhang Liangbin, Li Yuehua, et al. Non-rigid registration of MRI images of hysteromyoma. Microcomputer application, 2012 (12):1-4.

Wu Longyi, He Chuchu, Chen Yazhu. Design of ECG simulation front-end for exercise monitoring. Microcomputer application, 20 13, 29(04):5-7.

Li Jia, Xiong Ping, Gong Xia, et al. Ultrasonic manifestations of acinar cell carcinoma of parotid gland. Chinese journal of ultrasound in medicine, 20 14(5):385-387.

Wu, Sheng, Chen, etc. Radiation shielding method of high intensity focused ultrasonic probe. Engineering, 2015,26 (s1): s959-s966.

[29] Ding Angang, Chen Yazhu. Research progress of thermosensitive liposomes (TSL). Journal of Fudan University: Medical Edition, 2015,042 (002): 262-266.

Ding Angang, Xiong Ping, Shen Guofeng and Chen Yazhu. Comparative study on the therapeutic effect of hyperthermia at +0℃ and 43℃ combined with pegylated liposome adriamycin on rabbit VX2 tumor. Journal of Shanghai Jiaotong University (Medical Edition), 2016,36 (06): 799-802.

In 2002, Chen Yazhu published papers in the Proceedings of the Third National Congress and Academic Conference: Application of Adaptive Algorithm in Radio Frequency Ablation System, Power Amplification Technology of Phased HIFU Multi-array, and Research on Denoising Methods of Ultrasound Images in Focused Ultrasound Therapy System.

In 2004, Chen Yazhu published papers: Research on Spherical Focused Ultrasound Phased Array, Development of Radiofrequency Ablation Therapeutic Apparatus for Atrial Fibrillation, and Discussion on Mechanism and Related Issues of High Intensity Focused Ultrasound.

In 2004, Chen Yazhu published a paper in "Proceedings of the 6th Youth Academic Conference of China Instrumentation Society: Development of Counting Device to Characterize the Cleanliness of Medium and Abdominal Warm-hot Perfusion Chemotherapy Instrument".

In 2005, Chen Yazhu published papers: improved edge-enhanced diffusion and its application in AFM image analysis, parametric surface model study of acetabular cartilage, and numerical simulation analysis of HIFU treatment in Shanghai thermal field.

In 2007, Chen Yazhu published papers in the 2007 China Biomedical Engineering Progress-Proceedings of the Annual Meeting of China Biomedical Engineering (Volume I) held in Xi City, Shaanxi Province: B-ultrasound texture analysis and characterization of radiofrequency ablation tissue, three-dimensional finite element model for calculating thermal damage area in focused ultrasound surgery, and large-angle three-dimensional imaging system of human body based on synchronous scanning.

On 20 10, Chen Yazhu published a paper entitled "Promoting the Independent Innovation and Industrialization of Medical Devices in China" in the Proceedings of the 20 10 Annual Meeting of China Instrumentation Society, Fuzhou, Fujian.

In 2005, Medical Physics edited by Chen Yazhu was published by Higher Education Press.

20 13, 13 International Conference on Therapeutic Ultrasound was held in Shanghai Jiaotong University. The conference was jointly organized by the International Society of Therapeutic Ultrasound (ISTU) and the Chinese Society of Ultrasonic Medical Engineering. Chen Yazhu served as the president of the conference and delivered a keynote speech.

personnel training

Chen Yazhu's first requirement for students is to "learn to be a man" and have good moral character and character. The students said in a collective memory article, "The teacher told us many times that anyone and any information leaving the laboratory, whether publishing articles, speaking at seminars or even discussing at retreats, should be the most strict in academic ethics."

By May, 2020, Chen Yazhu has trained more than 10 postdoctoral students in biomedical engineering, more than 40 doctors and more than 100 masters. Among them are Bai Jingfeng and Shen Guofeng, associate professors of Shanghai Jiaotong University School of Biomedical Engineering, and Chea Chang, founder and dean of Shanghai Zhongqiao College of Nursing and Health.

Honor recognition

Personal life

Chen Yazhu, 1944 When she was 8 years old, her father fell ill and could not go to the hospital because of financial difficulties. Her teenage brother took her young life. In addition to her grief, she also sprouted the ideal of becoming a doctor when she grew up, treating poor patients. My mother, a well-educated woman, attaches great importance to children's education. Despite her poor family, she tried her best to send Chen Yazhu to a humble primary school in the countryside. Chen Yazhu understood her mother's intention of "golden phoenix flying out of the grass nest", studied hard and made unremitting efforts, and was admitted to Ningbo No.3 Middle School and Shanghai Women's Middle School successively. 1956 After graduating from high school, he was selected by the school as a preparatory student to study in the Soviet Union, so he failed to enter the medical school for further study. Later, due to the deterioration of Sino-Soviet relations, one year later, she was sent to the Department of Electrical Engineering of Shanghai Jiaotong University to study. During her college years, she studied hard and mastered basic theories and skills. From 65438 to 0962, she stayed in Shanghai Jiaotong University to teach and became the youngest teacher in the high-pressure teaching and research group at that time.

Personality assessment

From lithotripsy to magnetic wave knife and ultrasonic knife, she leads the interdisciplinary "intersection between doctors and patients" with her heart. Chen Yazhu: She has a good hand without being a doctor. (Wen Wei Po Review)

Chen Yazhu is one of the pioneers in the field of biomedical engineering and the development of large medical devices in China. Although she is over eighty years old, she is still committed to her career and her love and concern for her students. She is an elder, teacher and scholar deeply loved by teachers and students. (Audited by China Academy of Engineering)

Chen Yazhu, who is over eighty years old, is still committed to promoting the scientific and technological innovation plan of China medical device industry and leading the interdisciplinary development of biomedical engineering. She took the lead in practicing the innovative mode of "production, learning, research and application" which combines medical and industrial work and crosses medical and industrial work. As the first person to combine engineering technology with life and health in China, based on China's major national strategy and people's livelihood needs, she has made great contributions to the healthy China and the research and development of high-end medical devices in China. (Xinmin. com)

Personality influence

20 19, 10 In June, the launching ceremony of "Academician Chen Yazhu Fund of School of Biomedical Engineering, Shanghai Jiaotong University" was held at the 40th anniversary meeting of discipline construction of Shanghai Jiaotong University, initiated by Chen Yazhu.