Speaking of our feces, it may be inconspicuous, but it is likely to save lives. Because there are 10 to 1000 trillion microorganisms in our intestines, among which1000 is closely related to our health, because the changes of these microbial flora are closely related to the immune system, and "feces" is the representative that can best reflect the composition of intestinal microbial flora. This sounds a little hard to understand, but simply put, it is to transplant the good bacteria in the feces into the patient's intestines, so that the bad bacteria can be eliminated and the disease can be cured.
The 90-year-old grandmother was infected with Clostridium difficile, and her grandson donated feces to save her life. Clinically, a 90-year-old grandmother fell ill in a nursing home because of dementia and joint degeneration. Later, she coughed for a long time, was diagnosed as pneumonia by Kaohsiung Hospital, and even had recurrent diarrhea, even more than once a day 10. Later, she was diagnosed with Clostridium difficile, which is a legal infectious disease. Grandma is getting thinner and thinner, and antibiotic treatment has no effect. Finally, she decided to accept a "stool transplant". Granddaughter provides feces, and through colonoscopy and * * *, the feces are implanted into grandma's intestines, so that healthy microbial strains can grow, and grandma can successfully restore normal flora and healing function of large intestine mucosa. Clinically, a 70-year-old son donated feces to a 90-year-old father with ulcerative colitis, who recovered completely soon after implantation.
Wu, vice president of Zhonghe Memorial Hospital affiliated to Kaohsiung, said that this kind of "intestinal flora implantation" only needs to take feces from people with healthy intestines, dilute and mix them with normal saline, then remove impurities, and implant them into the intestines through the large intestine through colonoscopy, or from the upper digestive tract through nasogastric tube and gastroscope. Of course, feces also need to be tested, and hepatitis B, hepatitis C and major infectious diseases need to be excluded. Domestic donors give priority to relatives, and the transplant process takes only 30 minutes.
Vice President Wu explained that the current "fecal transplantation" technology is more effective than traditional drugs for recurrent Clostridium difficile enteritis. But it does not rule out that more and more diseases can use this method in the future. Even Britain has made healthy intestinal flora into drug capsules through pharmaceutical procedures, and has actually carried out clinical phase I human trials, which will be widely used in other diseases in the future.
In the future, fecal bacterial transplantation (FMT) will be used to treat various diseases.
Clostridium difficile infection, multi-drug resistant bacteria infection, autism, Parkinson's disease, inflammatory bowel disease, autoimmune disease, obesity and metabolic syndrome, a press conference was held at Zhonghe Memorial Hospital affiliated to Kaohsiung Medical University, fatal!