1, the symptoms are different: the patient is conscious when he opens his eyes, but his eyes can't be controlled, and he has symptoms such as nystagmus and gaze. When he closes his eyes, he is unconscious, his eyes are closed and he doesn't respond to external stimuli.

2. Different treatment methods: For patients with open eyes, specific immune reactions or antigens need to be treated, while for patients with closed eyes, different treatment methods need to be adopted to restore consciousness.