Comrade Ma Xu won many scientific and technological awards, such as the National Outstanding Scientific and Technological Achievement Award in the Ninth Five-Year Plan and the First Prize of Scientific and Technological Progress of the National Family Planning Commission. In addition, the research on new methods of non-invasive prenatal diagnosis and the exploration of new methods of prenatal genetic diagnosis of genetic diseases were also rated as the top ten scientific and technological achievements of family planning/reproductive health in China during the Ninth Five-Year Plan period by the National Family Planning Commission. In China, he initiated a series of scientific and technological research on new technologies and methods of non-invasive prenatal diagnosis, published many academic papers and obtained many invention patents; In the prevention and control of Down's syndrome, the most common hereditary mental retardation in human beings, serological screening and dried blood smear screening techniques were established in the first and second trimester, and the only database that can be used for clinical risk discrimination in China was built, with a total of 80,000 pregnant women screened and corresponding national standards established. Experts at home and abroad are being organized to compile academic monographs in this field. In the prevention and control of congenital rubella syndrome, a seroepidemiological survey was carried out in the main representative areas of the country (including cities, rural areas and pastoral areas). ), and found out the population distribution of rubella virus antibody titer of women of childbearing age in China for the first time. A method for measuring rubella virus immunity of women of childbearing age was successfully developed, and the corresponding national standard was formulated and officially applied. At the same time, a comprehensive pilot study of community intervention technology for congenital rubella syndrome was carried out in Shenzhen. On this basis, a three-level network of birth defect intervention in Shenzhen was established, which realized the networking of technical management. The project won the second prize of Shenzhen Science and Technology Progress Award. In addition, Comrade Ma Xu has done a lot of research on the application of non-invasive prenatal diagnosis technology in preventing Rh blood group incompatibility between mother and fetus, searching for screening markers for breast cancer, ovarian cancer and cervical cancer, and establishing new methods. He has published many papers and obtained many invention patents.

Finally, during the epidemic of atypical pneumonia in China, Comrade Ma Xu led his research team to establish the differential diagnosis technology of eight common viruses causing atypical pneumonia, including SARS coronavirus. According to the technical requirements promulgated by the State Administration of Pharmaceuticals, clinical trials were conducted in conjunction with the General Hospital of the People's Liberation Army, Xiaotangshan Field Hospital, Peking University First Hospital and Union Medical College, and invention patents and software copyrights were formed, which were formally declared to the State Administration of Pharmaceuticals. This product is the only product that can be used for differential diagnosis of SARS pathogens in China, and its clinical trial results have been specially introduced at the WHO SARS International Conference. In a word, Comrade Ma Xu's academic research fields range from the etiology of birth defects and major reproductive health diseases, the research and development of key prevention and control technologies, the industrialization of biotechnology drugs, prevention and control programs to the research of corresponding technical standards, thus forming a scientific and technological innovation chain focusing on birth defects intervention and prevention and control of major reproductive health diseases.

In the transformation and industrialization of scientific and technological achievements, Comrade Ma Xu paid special attention to the transformation of scientific and technological achievements into real productive forces. The technology of Rh blood group diagnosis for mother and baby 1 item has been transformed into 6 million yuan, and on this basis, an experimental base meeting the national standards for biotechnology product development has been established, laying a foundation for further research and development of biotechnology products related to reproductive health. The prenatal diagnosis project developed by Comrade Ma Xu registered a biotechnology company in Zhongguancun High-tech Industrial Park, and served as the company's chief scientist, directly leading the transformation and industrialization of independent series of biotechnology high-tech patent achievements. The company has been recognized as a high-tech enterprise in Beijing by Beijing Science and Technology Commission, and it is also the undertaking unit of the national "Tenth Five-Year Plan" scientific and technological research project. Among them, Down's syndrome prenatal screening system has completed170,000 clinical trials, and reported to the State Administration of Medical Products at the same time. In the birth defect intervention engineering technology research center of the National Population and Family Planning Commission, a differential diagnosis system for SARS pathogens has been developed, and an invention patent has been applied, which has entered the declaration procedure. In terms of cooperation with domestic and foreign biotechnology companies, there are horizontal cooperation projects with internationally renowned biotechnology companies such as the United States and Japan, as well as horizontal cooperation projects with well-known domestic biotechnology companies, which greatly promotes the transformation and industrialization of scientific and technological achievements. In terms of scientific and technological management and institutional innovation, Comrade Ma Xu took the lead in implementing a number of enterprise management measures, such as appointment system, incentive and elimination mechanism, and full-cost accounting management, and set up full-time personnel for intellectual property and human resources management. There are only 4 regular staff members in the center, including external scientific and technical personnel 15 (including 3 professors and 2 doctors), 3 external managers, 3 graduate students 13 and 3 doctors. Comrade Ma Xu tried to further explore the transformation ways of scientific and technological achievements that conform to the laws of market economy and the development of science and technology itself, improve the level of scientific and technological management with institutional innovation, and promote scientific and technological innovation with institutional innovation, so as to finally realize a virtuous circle of talent, technology and economic operation.