Ingredients: S- adenosylmethionine (SAMA)

Nutramax from Nutrilite Martens, USA

Dosage: 20 mg/kg/day

1. function

Methyltransfection of 1. 1: Participating in phospholipid synthesis is very important for the structure, fluidity and function of cell membrane.

Transthiolation of 1.2: It is the precursor of glutathione and is synthetic. Glutathione is a powerful antioxidant, which is involved in many metabolism of the body and detoxification of the liver. It is an important liver detoxification and helps to maintain the function of liver cells. When the liver is damaged, endogenous glutathione decreases, thus affecting liver function.

Transamination of 1.3: aminopropyl plays an important role in the production of anti-inflammatory substances, protein and DNA, and promotes cell replication and liver tissue renewal.

1.4SAMe has the effects of anti-inflammation, analgesia and tissue repair, and has obvious curative effect on joint diseases, promoting cartilage generation and relieving joint pain, stiffness and swelling. In Europe, SAMe has been used as a prescription drug to treat arthritis.

Step 2 use

This product is an enteric-coated film tablet, which must be taken completely on an empty stomach, 1 capsule in the morning and evening, 1 hour before meals or 4 hours after meals. Do not break, break, chew or dissolve.

In order to prevent the drug from refusing to eat, a small amount of soft food can be packaged for administration; If you take it with food, please double it. According to the needs of pets, the number of tablets can be gradually reduced or increased at any time. Many pets have to take DenosylTM for a long time according to the maintenance amount, which is the normal dosage 1/3.

At present, it is the first choice for American veterinarians to treat various liver diseases in dogs and cats. Its main function is to repair damaged liver cells, eliminate ascites, restore normal gallbladder function, reduce jaundice and promote dogs and cats to take the initiative to eat. Can play an important role in a short time.

2. Dinamarin liver-protecting tablets 90 and liver-protecting tablets 225mg?

Ingredients: s- adenosylmethionine, silymarin.

Nutramax from Nutrilite Martens, USA

1 effect

Liver protection function of 1. 1: It has strong antioxidant function, protects liver cells from free radicals and captures free radicals, which is far more effective than vitamin E and strengthens the detoxification function of the liver.

1.2 can prevent liver cirrhosis and hepatitis, increase bile flow and promote digestion and absorption of intestinal nutrition.

1.3 can promote the synthesis of protein, accelerate the production of new liver cells, or make damaged liver cells repair themselves and increase the level of glutathione. Therefore, it is called "natural liver protection drug".

Anti-tumor effect of 1.4: All kinds of reactive oxygen species can oxidize guanine to form 8- antelope guanine, causing DNA damage and then causing tumors. The application of antioxidants, especially free radical scavengers, can prevent this process.

Step 2 use

2. 1 Take it on an empty stomach (at least before meals 1h or 4h after meals).

2.2 Hugan Qiangqiang Tablet 90mg: sugar-coated tablet to protect it from stomach acid damage. Can not be broken, it will affect intestinal absorption. If feeding is not easy, you can wrap it with a small amount of food, but try to avoid it or increase it appropriately.

2.3 Hugan Jiangan Tablets 225mg Chewable Tablets: It adopts embedding technology, can be divided and is not easy to be oxidized. It is not recommended to add it to water or syrup.

2.4 Its additive silymarin may cause gastrointestinal reaction (vomiting or diarrhea).

Three. Ntoni Zentoni

Ingredients: S- adenosylmethionine, lecithin.

French Zeng Tornier

1. function

Lecithin is called "the third nutrient" alongside protein and vitamins. Nourishing myocardium and regulating blood lipid level means lowering cholesterol level and protecting liver.

Step 2 use

Because its main component is also S- adenosylmethionine, it must also be taken on an empty stomach. However, its processing adopts microencapsulation technology to prevent biochemical reaction, and its enteric coating has good palatability and can be divided, crushed or chewed.

Fourth, Fonzgan heparin.

1. Composition and function

Analysis and comparison of drugs used for liver diseases in dogs and cats

Step 2 use

Suggested dosage: take one capsule every 5 kg body weight every day during the health care period, and the dosage can be adjusted 2-3 times according to the situation.

It is suitable for liver health care when liver index increases, acute and chronic hepatitis, poisoning, fatty liver and other liver injuries and chronic diseases are treated with drugs for a long time.

Note: There is little or no silymarin in conventional liver protection drugs with the same composition. (The dosage of silymarin for adjuvant treatment of liver diseases is 20-50mg/kg/d) Fengzi Liver can provide vitamin B group (necessary for transforming it into glutathione) and higher dosage of silymarin. Fengzigan combined with Danuo, Huganjian Yuanbao or Endotoni is more effective.

Five, Ganxinsu

Ingredients: taurine, L-carnitine, vitamin E, coenzyme Q 10, essential fatty acids (DHA and EPA).

South Korea

1. function

Taurine: an essential amino acid for cats. Taurine can combine with bile acids to form taurocholic acid, which is necessary for digestive tract to absorb lipids, relieve bile obstruction and increase bile flow. It is also used to maintain muscle contractility, neutralize free radicals and resist oxidation. It can improve myocardial contractility, delay myocardial failure and maintain normal retinal function.

1.2 L-carnitine: It is an essential amino acid to maintain normal nutrition and fat metabolism, which can enhance myocardial energy, improve myocardial contractility and maintain the normal function of the heart. Can strengthen lipid metabolism and treat fatty liver.

1.3 vitamin e: antioxidant, which can inhibit myocardial damage caused by free radicals and delay myocardial failure.

1.4 coenzyme Q 10: Improve myocardial function, lower cholesterol and lower blood pressure.

stand treat

2. 1 heart: improve the contractility of animal heart, treat dilated heart disease, improve cardiac insufficiency, protect blood vessels and prevent thrombosis.

2.2 Liver: Mainly aimed at fatty liver and cholestasis, promote bile secretion, and then improve liver function. It is not effective for other liver diseases.

2.3 Other aspects: lowering cholesterol, enhancing immunity and strengthening muscles.

? 3. Dosage and usage: 10kg or less, twice a day, each time 1 tablet. /kloc-above 0/0kg, twice a day, 2 tablets each time. Preferably mixed with essential fatty acids.

Vi. Gatorade Glucolactone

1. function

Pharmacological action: This product can be combined with poisons containing hydroxyl or carboxyl after entering the body to form a low-toxic or non-toxic combination, which is excreted in urine and has the function of protecting liver and detoxifying. In addition, glucuronic acid can also increase the content of liver glycogen and reduce the storage of fat.

After the drug enters the body, the lactone ring is opened under the catalysis of enzyme and converted into glucuronic acid, which is one of the important detoxification substances in the body. In addition, under the action of glucuronosyltransferase, it can be combined with metabolites, poisons or drugs containing phenolic groups, hydroxyl groups, carboxyl groups and amino groups in the liver or intestine to form nontoxic glucuronic acid conjugates, which are excreted with urine. But cats are relatively deficient in glucuronosyltransferase.

2. Note:

The application of Gantaile in cats is basically ineffective, but it will increase the metabolic burden of the liver.

Dogs can be used for adjuvant treatment of acute and chronic hepatitis in dogs and toxic hepatitis caused by food or drugs.

? 3. Dosage: 50-200mg/ each, taken orally, 2-3 times a day.

100-200mg/ time, intramuscular injection or intravenous drip, daily 1 time.

? Seven. Gan Bao capsule

Ingredients: Radix Bupleuri, Rhizoma Cyperi, Radix Curcumae, Radix Angelicae Sinensis, Atractylodis Rhizoma, Fructus Schisandrae Chinensis, Radix Astragali, Radix Paeoniae Alba, Poria, Herba Artemisiae Scopariae, Radix Isatidis, Radix Glycyrrhizae, etc.

? ? 2. Function: Soothing the liver and regulating qi, clearing away heat and dissipating stagnation, softening the liver and strengthening the spleen, regulating qi and blood, and lowering transaminase, which is used for acute and chronic hepatitis and early cirrhosis.

3. Dosage: 1 capsule/10kg twice a day, 1 month is 1 course of treatment.

Eight, liver and kidney health

1. Ingredients: extracts from various natural plants such as Chuanxiong and Astragalus.

2. Function: clearing away heat and toxic materials, protecting liver and kidney, improving immunity, promoting diuresis and removing stagnation, diuresis and dehumidification, warming intestine and astringing lung.

3. Dosage: oral or drinking, 1ml/kg,/kloc-0 once a day, for 3-5 days.

Overview of oral drugs

Analysis and comparison of drugs used for liver diseases in dogs and cats

Nine, liver complex peptide

This product is a small molecular multi-skin active substance extracted and purified from fresh suckling pig liver, which has the following biological effects:

1. can obviously stimulate the DNA synthesis of newborn hepatocytes, promote the recovery of mitochondria and rough endoplasmic reticulum of damaged hepatocytes, promote the regeneration of hepatocytes, accelerate the repair of liver tissue and restore liver function.

2. Improve the phagocytic function of kupffer cells in liver, prevent the toxin from intestinal tract from further damaging liver cells, and inhibit the activity of tumor necrosis factor (TNF), thus promoting the repair of liver necrosis. At the same time, it can reduce transaminase, serum bilirubin and shorten prothrombin time.

Dosage: 2-3 mg/kg, intramuscular injection or intravenous injection for dogs and cats.

X.3AA

Ingredients: leucine, isoleucine, valine.

These three amino acids are branched-chain amino acids, and the side chains in the three molecular structures all have branched structures. It is mainly metabolized in skeletal muscle.

1. Role:?

(1) Valine, leucine and isoleucine are all branched-chain amino acids, which can correct the imbalance between branched-chain amino acids and aromatic amino acids in plasma and prevent hepatic coma caused by excessive concentration of aromatic amino acids in brain.

(2) It can promote the synthesis of protein, reduce the decomposition of protein, promote the regeneration and repair of liver cells, and improve hypoproteinemia.

(3) directly metabolize energy in muscle, fat, heart, brain and other tissues for the body to use, thus reducing the burden on the liver. ?

2. Applicable to: hepatic encephalopathy, severe hepatitis, liver cirrhosis and chronic active hepatitis caused by various reasons. It has a good effect before and after hepatobiliary surgery.

Dosage: dogs and cats 10 ml/kg/day.

Xi。 Yinzhihuang

1. Ingredients: Herba Artemisiae Scopariae, Fructus Gardeniae, Radix Astragali and Flos Lonicerae extract.

Herba Artemisiae Scopariae: It can promote bile secretion and bile acid and bilirubin excretion.

Gardenia: It can promote bile secretion and inhibit the rise of bilirubin in the blood.

Baicalin: It can be used for damp-heat jaundice and has broad-spectrum antibacterial effect.

Honeysuckle: It has broad-spectrum antibacterial and anti-influenza effects.

2. It has the effects of clearing away heat and toxic materials, promoting diuresis and eliminating jaundice, and reducing alanine aminotransferase.

Applicable objects: Both dogs and cats can be used for acute, persistent, chronic and severe hepatitis, and can also be used for comprehensive treatment of other severe hepatitis.

3. Usage: 10% glucose injection 250~500ml diluted and then dripped.

Part two? Liver disease formula granules

A, royal liver prescription grain

Reducing copper content and increasing zinc content can minimize the accumulation of copper in hepatocytes and intracellular damage caused by cholestasis.

Restricting sodium intake can reduce portal hypertension and reduce the accumulation of extravascular fluid.

Synergistic antioxidant complex can slow down the degeneration of hepatocytes.

Protein, a plant with high energy and high absorption, can reduce the burden on the liver and limit the occurrence or deterioration of liver diseases.

Analysis and comparison of drugs used for liver diseases in dogs and cats

Second, the hills (length/width)

Appropriate content of digestible high-quality protein is helpful to reduce the burden of liver function and maintain liver function.

The added L-carnitine helps to maintain normal fat metabolism in the liver.

Adding antioxidants (such as vitamins E and C) helps to control cell oxidation and maintain a healthy immune system.

Low sodium helps to maintain normal blood pressure.

Can be used for treating hepatitis, biliary liver disease, hepatic encephalopathy and fatty liver.

Taboo: hyperlipidemia, pregnancy.

Article source: Dr. Wang Lili from Ornamental Animal Hospital