Breaking the international monopoly and focusing on hyaluronic acid research for 39 years
The content of hyaluronic acid in human body is about 15g, which plays an important role in human physiological activities. The decrease of hyaluronic acid in tissues and organs will lead to arthritis, arteriosclerosis, pulse disorder and brain atrophy. The decrease of hyaluronic acid in human body will lead to premature aging.
Before 1990s, hyaluronic acid was mainly extracted from Celosia cristata in China, with limited raw materials and high cost. At the same time, hyaluronic acid exists in animal tissues in the form of complex with protein and other polysaccharides, so the separation and purification process is complicated, the yield is low, and the productivity is very limited. During that time, domestic hyaluronic acid mainly depended on imports and was once monopolized by the West.
As early as 1983, Ling Peixue devoted herself to the research and development of hyaluronic acid. In order to realize the localization of hyaluronic acid, the research team represented by Ling, after hundreds of experiments, finally took the lead in inventing the biotechnology fermentation to produce hyaluronic acid in the mid-1990s, realizing the large-scale production of hyaluronic acid in China and pushing it to the world, and was awarded "the father of hyaluronic acid in China" by China Biopharmaceutical Industry Association.
The hyaluronic acid theory and technology system and product quality he created reached the international advanced level, and the hyaluronic acid technology was applied to the medical field, treating tens of millions of patients in ophthalmology, orthopedics and dermatology, making an important contribution to the development of medical undertakings in China. China has become a powerful country in the field of hyaluronic acid, and Ling's contribution is indispensable.
Academician Ling focused on hyaluronic acid for 39 years and persisted in scientific research for decades. It has more than 300 patents at home and abroad, and has won 2 second prizes of national scientific and technological progress, 1 third prize, ho leung ho lee foundation Science and Technology Innovation Award, Shandong Science and Technology Highest Award and China Youth Science and Technology Award. Academician Ling has also been selected as a national outstanding professional and technical personnel and a young and middle-aged expert who has made contributions to the country for many times. He won 4 national awards, more than 20 provincial and ministerial awards, and published more than 65,438,000 academic papers.
202 1, Ling was elected as an academician of the International Eurasian Academy of Sciences, the only academician in the field of hyaluronic acid.
Billion-level food-grade hyaluronic acid new track opens
202 1 1 7, the national health and wellness commission issued a document, approving sodium hyaluronate (commonly known as hyaluronic acid) as a "new food raw material", which can be applied to ordinary food additives.
Wang Mark, a professor at Tsinghua University College of Pharmacy and director of the Institute of Pharmacology, together with the authors of Basic Medical College of Capital Medical University and Clinical Nutrition Department of Peking Union Medical College Hospital, published a paper "Research Progress on Physiological Function and Mechanism of Oral Hyaluronic Acid" in Food Science.
The paper points out: "It is preliminarily proved that oral hyaluronic acid plays an important role in maintaining skin health, repairing joint injuries, regulating intestinal immunity and relieving dry eye. It has a certain protective effect on human skin, eyes and joints. Oral hyaluronic acid can increase the moisture content in skin after ultraviolet irradiation, and finally achieve the effect of improving skin condition and slowing down skin aging. "
Regarding oral hyaluronic acid, Academician Chen Jian of China Academy of Engineering publicly stated that research shows that after gastrointestinal chemical digestion and partial enzymolysis, part of sodium hyaluronate is absorbed by human body, which helps to maintain the hyaluronic acid content of human body. In addition, oral administration of 120 mg and 200 mg sodium hyaluronate every day can protect gastrointestinal health, protect eyes, relieve osteoarthritis and improve skin.
According to the research report of Essence Securities, hyaluronic acid is expected to be used as food raw materials together with collagen, astaxanthin and other ingredients in the future, and different combinations or dosage forms will be introduced according to consumers' preferences, which will be applied to downstream functional foods such as milk and dairy products, beverages, chocolate products and candy.
Hyaluronic acid food has become a new way out and track since it was approved in 202 1. Essence Securities predicts that the medium and long-term market space of domestic food-grade hyaluronic acid terminal products is expected to reach 654.38+054 billion yuan, among which, Guoxianmei has become one of the first batch of technology enterprises to eat crabs in the hyaluronic acid food field.
Yueyanxiu 1 Sugar, the New Dark Horse of Oral Hyaluronic Acid
At the beginning of its establishment, Guo Mei formulated a medium-and long-term strategy based on "hyaluronic acid+". Through strong cooperation with top scientists of hyaluronic acid, Guo Mei has built an integrated platform of "hyaluronic acid+"in Industry-University-Research. The strategic cooperation with Academician Ling officially kicked off the strategy of "Hyaluronic Acid+"of National Fiber Beauty.
Yueyanxiu 1 candy owned by National Delicious adopts the latest scientific research achievements and latest patented technology of Academician Ling-full molecular weight hyaluronic acid Gauss HA. Through enzyme engineering cutting, gradient photothermal treatment and low-temperature drying, large, medium and small hyaluronic acid molecules are evenly distributed, and through the synergistic mechanism, the whole molecule hyaluronic acid and these effective components are quickly absorbed by human skin, joints, eyes and other parts, thus achieving anti-aging repair and anti-aging effects.
"The whole molecule hyaluronic acid is distributed in a balanced way, and penetrates into the cell membrane through precise slow release, controlled release and long-term absorption, thus achieving a sustained and long-term health care effect." Wei Wei, CEO of Fruit Delicious, said, "Yueyanxiu 1 Candy has added active ingredients such as ascorbic acid, fish peptide collagen peptide, resistant dextrin, yeast extract, γ-aminobutyric acid and so on in addition to full molecular weight hyaluronic acid, which can achieve good anti-aging health care effect under the comprehensive action of active ingredients."
In the past fifteen years, Wei Wei has led the team to manage more than 3,000 large health stores since she set up a stall, and accumulated rich experience in offline channel expansion and store management. 202 1, Wei Wei further amplified her own advantages, made strategic cooperation with Academician Ling, the father of hyaluronic acid, and accurately laid out the strategy of "hyaluronic acid+".
The strategic cooperation with Academician Ling ensures the safety, health and strong efficacy of the products, and the strong ability to expand offline channels will help Guomei open up a new offline health market, which is an area neglected by hyaluronic acid giants.
Strong R&D genes and leading channel advantages constitute the core competitiveness of COFIMA. Wei Wei said that Fruit Delicious will further build the "Hyaluronic Acid+"Industry-University-Research platform, become the world's leading hyaluronic acid technology enterprise, and use high-quality hyaluronic acid products to benefit people's health.