GHb can effectively reflect the blood sugar control of diabetic patients in the past 1 ~ 2 months. GHb is composed of HbA 1a, HbA 1b and HbA 1c, of which HbA 1c accounts for about 70%, and its structure is stable, so it is used as a monitoring index for diabetes control. HbA 1c was determined by affinity chromatography or high performance liquid chromatography, and the normal value was 4% ~ 6%.
If glycosylated hemoglobin >: 9% indicates that patients with persistent hyperglycemia will have complications such as diabetic nephropathy, arteriosclerosis and cataract, which is also a high risk factor for myocardial infarction and stroke death.
Extended data
Glycosylated hemoglobin is formed by a slow, persistent and irreversible glycosylation reaction, and its content depends on the blood sugar concentration and the contact time between blood sugar and hemoglobin, but has nothing to do with the blood drawing time, whether the patient fasted or not, and whether insulin is used.
Glycosylated hemoglobin is the gold standard to measure blood sugar control, and it is also an important means to diagnose and manage diabetes. In the treatment of diabetes, glycosylated hemoglobin level is of great clinical significance for evaluating the overall control of blood sugar, finding the problems in treatment and guiding the treatment plan.
Blood sugar rises under stress conditions such as cerebrovascular emergency, but glycosylated hemoglobin does not rise. It is not enough to measure blood sugar only for gestational diabetes. Controlling glycosylated hemoglobin is more meaningful to avoid macrosomia, stillbirth, teratoma and preeclampsia.
References:
Baidu encyclopedia-glycosylated hemoglobin