Zhuang Xiaowei, 1972- 1 Born in Rugao City, Jiangsu Province, China, is a biophysicist, a member of the American National Academy of Sciences, a member of the American Academy of Arts and Sciences, a foreign member of the China Academy of Sciences, and a double-employed professor of chemistry and chemical biophysics at Harvard University.
Zhuang Xiaowei's main research work is to develop and use single molecule biology and biological imaging technology and ultra-high resolution biological imaging technology to study biomolecules and their molecular assembly processes in vitro and in living cells.
Zhuang Xiaowei didn't win the Nobel Prize because Zhuang Xiaowei's research team filmed the process of a single virus invading cells, which is the first time in the history of science. STORM technology independently invented by Zhuang Xiaowei's research group uses laser to "light" or "extinguish" fluorescence in cells, and then takes photos. Only one position in the cell is "lit" or "extinguished" at a time. Like progressive scanning, the images of cells are recorded bit by bit, and finally a complete high-resolution image is obtained by superimposing multiple images. The paper published by Zhuang Xiaowei shows that the resolution can reach 20 nanometers, but unfortunately it didn't win the Nobel Prize in the end.