2) Interaction between small drug molecules and biological macromolecules

biographical notes

Educational background:

1993.9–1997.7 Department of Chemistry, Hebei Normal University, majoring in chemical education, undergraduate.

1997.9–July 2000, majoring in organic synthesis, Department of Chemistry, Hebei Normal University.

September 2000–July 2003, majoring in physical chemistry, Institute of Chemistry, Chinese Academy of Sciences, Ph.D.

Work experience:

July 2003–July 2005, postdoctoral fellow, Institute of Chemistry, Chinese Academy of Sciences.

July 2005-July 2006, Lecturer, School of Life Science and Technology, Beijing Institute of Technology.

July 2006-Associate Professor, School of Life Science and Technology, Beijing Institute of Technology

research results

Mainly engaged in chemical biology research. The synthesis and activity of porphyrin -5- fluorouracil antitumor drugs, the synthesis of porphyrin-ruthenium bipyridine, porphyrin-amino acid and other photosynthetic simulation systems, and their photochemical and photophysical properties were studied successively. Recognition interaction between small molecular compounds (including vitamin K3, 2- aminopurine, oligoamide, porphyrin derivatives, etc.). ) and DNA Good work has been accumulated in the field of chemical biology, especially in the interaction between small chemical molecules and biological macromolecules. Published 8 SCIentific research papers 10 in the above research fields, including sci papers 10, the first author10. The main research direction is the design, synthesis and interaction of selective recognition molecules for DNA G4 structure.