1985 graduated from Changchun Institute of Applied Chemistry, Chinese Academy of Sciences in July.
Main research interests: bioorganic chemistry, enzymology.
Main job resume:
65438+June 0975-65438+March 0978: Youth Entrepreneurship Team Work in Yangdachengzi Town, Gongzhuling City, Jilin Province.
65438+March 0978-65438+August 0982: biochemistry major, Department of Chemistry, Jilin University.
65438+August 0982-65438+July 0985: Graduate student majoring in polymer, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences.
65438+July 0985-65438+September 0996: Work of the State Key Laboratory of Enzyme Engineering of Jilin University.
1September 1996 to present: worked in the biochemical room of the Department of Applied Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University.
Main research direction: bioorganic chemistry (enzymatic reaction and its application).
The main course taught: biochemistry, a basic course for undergraduate students in chemistry department, lasts for 54 hours.
Scientific research projects undertaken:
1. "Technical Research on Treating Phenol-containing Wastewater with Immobilized Enzymes" Basic Research Project of Guangzhou Science and Technology Commission 1998 165438+2000 10-65438+February, project leader.
2. Existence and Biological Significance of Effective Components in Medicinal Plants, Guangdong Provincial Foundation, 1999 65438+2002 10-65438+February. Main participants.
3. The national fund project "Study on chemical model of biological oxidation-Michael addition and its chemical and biological significance",19991-2001,with main participants.
4. "Research on Chemical Synthesis of Hypoglycemic Drugs", a federal pharmaceutical cooperation project, funded by 654.38 million yuan from March 2000 to February 2000, mainly attended by participants.
Awards:
1. 1990 advanced worker of Jilin University.
2. 199 1 Jilin university advanced worker.
3. 1993 advanced workers of Jilin University.
4. 1994 won the 4th China Youth Science and Technology Award.
Business expertise:
Biotransformation in organic synthesis, separation and purification of protein and enzyme, immobilization of enzyme and cell, chemical modification of enzyme and protein, enzymatic reaction and its application (enzymatic organic synthesis in non-aqueous medium), biopharmaceuticals.
Office telephone number: 020-84 1 13690.
E-mail: CEDC 14@zsulink.zsu.edu.cn
List of major projects:
1. Regulation of synthetic diversity on lactate dehydrogenase activity 750, 75, 1995 ann. n. y. acad sci (included in SCI) Author: L.Ma, Z.J.Li 。
2. "Specific transformation of L-aspartase in the presence of alcohol" 750, 134. 1995. Journal of new york University (included in sci) Author: L.MA, B.X.Yan, H.T.
3. The Im mobility of prostaglandin synthesized by hydrophobic adsorption is 56,223, 1996. Additional biochemistry. Biotechnology. (included by SCI) Authors: Ma Xiaodong, Wang Xiaodong, Tang Xiaodong, etc.
4. Enzymatic Detoxification of AFA Toxin by Armillaria mellea B 1 Part III: Immobilized Enzymatic Detoxification, 864,592-599, 1998.ann.n.y.acad.sci (included by sci) D.L.
5. Synthesis of Substituted 1, 2- benzoquinone and Substituted 3- hydroxy -4( 1H)- pyridone: Application of Oxidation-Michael Addition in Organic Synthesis 17(4):377-383,1. China Journal of Chemistry (included by SCI), Li Mingsheng, Mary, Zhang Xiaozhong, etc.
6. Effect of p-phenyl aggregation on enzymatic polymer synthesis in dioxin/water mixture 33, 2339-2345,1995.j. Polymer Science: Part A: Polymer Chemistry. (included by SCI). Authors: Liu Wei, Ma, et al.
7. A novel organic solvent immobilized lipase and its structural model 200 (1): 83, 1994. Biochemistry and biophysics communication. (included by SCI) Authors: Yang, Cao Shaoguo, Ma et al.
8. Synthesis of 6-Substituted 3- hydroxy -4( 1H)- pyridone: Oxidation-Michael Addition of 3- hydroxy -4( 1H)- pyridone 55(8):2237-2244, 1999. (included by SCI) Li Mingsheng, Gu Liqun, Huang Zhisheng, Ma Er, etc.
9. Factors affecting the polymerization rate of phenolic substrate catalyzed by peroxidase in non-aqueous medium, 1 1 (1), 95, 1995. Journal of biochemistry, by Marin et al.
10. Study on the Enzymatic Polymerization of p-hydroxybenzene and p-phenylenediamine and Their Properties 29 (Supplement): 165, 1998. Functional materials, Marin, Huang Zhongli.
1 1. Study on the catalytic properties of horseradish peroxidase in dioxane aqueous solution 37 (Supplement): 53, 1998. Journal of Sun Yat-sen University, by Ma Lin, Huang Zhongli.
12. Enzymatic Synthesis of Functional Polymer Materials 7 (5): 14- 15, 1999 Fine and Special Chemicals, Marin.
13. bioorganic chemistry, edited by Ma Lin, published by Higher Education Press in June, 1998.
Contents of teaching/scientific research achievements:
1. aflatoxin B 1 The research on biological enzyme detoxification was appraised by the expert group chaired by Guangdong Science and Technology Commission,1July, 998. Researchers: Yao Dongsheng, Liu Daling, Gu, etc.
2. patent: preparation of pyridine 3,4-diketone derivatives and their medical uses (application number) No.98113271.5, application date:1July 1998. Gu, Li Miaosheng, Huang Zhishu.