Just when Zhang was in his twenties, his mother got a stubborn disease of wind arthralgia, which was cured for a long time and deeply stimulated the young Zhang. Zhang knew the importance of medical treatment and decided to abandon Confucianism and become a doctor. After studying the classics of traditional Chinese medicine and the writings of famous scholars in past dynasties, and learning from local old Chinese medicine practitioners such as Yu Deyan, Hou Chunlin and Wumen famous doctor Huang Yiquan, in recent years, medical skills have made great progress, and more and more people seek medical treatment. In order to further his studies, he studied under Zhu Langxian, a famous doctor in Tai Fang, Huang Qiang. Zhu regarded Zhang as his favorite pupil and pointed out his life experiences one by one. Zhang's knowledge is becoming more and more exquisite. Three years later, he made a horse in the city to help the world. Zhang is modest and humble. His clinic poster only says "Zhang knows medicine", not subjects. Because of his superb medical skills and serious responsibility for patients, he soon became famous in Jiading, and there was an endless stream of doctors and patients. Zhang has the ambition to revitalize Chinese medicine. In order to train successors, he worked tirelessly in Lanxi College of Traditional Chinese Medicine 15 years, writing books and teaching at night, often at night and sometimes until dawn. His works include 25 kinds and 66 volumes, including Selected Readings of Lanxi Medical Words and Justice of Seeking Medical Materia Medica. In the book "Materia Medica Justice", he has his own unique views and plays on many drugs. Zhang Zhixue is rigorous and constantly improves his works. When seeking medical treatment was revised for the third time, he was addicted to it and remained meticulous. He died shortly after the revision.