For patients with negative E antigen, the recurrence rate of treatment is relatively high. European and American countries suggest that surface antigen disappear or stop surface antigen seroconversion, but few people can meet this standard. Personally, I think that for chronic hepatitis B with negative E antigen, in principle, drug withdrawal can be considered after consolidation treatment for more than 2 years after HBV DNA turns negative, but the course of treatment should not be less than 3 years. However, liver function and hepatitis B virus content were examined at 1, 2, 3 and 6 months after drug withdrawal, so as to guard against the rebound of hepatitis B virus and seriously damage liver function. Therefore, your illness cannot be stopped. Whether adefovir has an effect on the fetus has no relevant clinical data. Personally, I suggest that you can switch to telbivudine before 6 months of pregnancy. Telbivudine has been tested in animals and has no effect on embryos, but there is no relevant experimental data in humans. It is recommended to consult a specialist in a specialized hospital. Reply expert: Beijing You 'an Hospital-Department of Integrated Traditional Chinese and Western Medicine-Deputy Chief Physician Hu Jianhua View the original >>