Around 2300 BC, Enkhduanna lived in Akkad region (in today's Iraq) in the northern part of the two river basins. She is the daughter of sargon (sargon, King Aga in the Bible), the founder of Akkadian Kingdom, and Tashlurtoum, the queen, namely Princess Akkad. She is the earliest temple priestess in the ancient civilization of the two rivers, and the first signing writer in the history of world literature so far, so she is praised as "Shakespeare of Sumer" by William Harrow, a famous American Assyrian scientist.

As the first writer in the history of civilization, Anhedoyana's humanistic expression in despair embodies the artistic creation characteristics of Mesopotamia. The history related to her also provides clues for investigating the rise and fall of human civilization.

The two river basins called Mesopotamia by the Greeks (Euphrates and Tigris), that is, today's Iraq, produced many first achievements in human history.