Newton was an epoch-making figure, and almost all disciplines made epoch-making contributions in his time. Although his genius, diligence and achievements are admired by the world today, they are limited by historical conditions, thus leaving a broad development space for future generations. His theoretical mechanics, calculus, the thought of matter composition, the discovery and theory of optical experiments, the law of universal gravitation, the three laws of motion, the law of low-speed fluid resistance, the theory of comets, the theory of tides and the system theory of the universe have all left epoch-making and fundamental contributions in the history of various disciplines.